Sentences with phrase «ends of chromosomes from»

Normally these vital end caps protect the loose ends of chromosomes from being chewed up or joined together, but are themselves whittled down every time the cell divides.

Telomeres are repetitive sequences of DNA that protect the ends of chromosomes from deteriorating.

These mutations deactivate the POT1 gene that protects the ends of our chromosomes from damage.

These DNA repeats are part of the protective capping structures, termed «telomeres,» which safeguard the ends of chromosomes from unwanted and unwarranted DNA rearrangements that destabilize the genome.

Telomeres are bits of DNA that protect the ends of chromosomes from unraveling or degrading.

Telomeres, compound structures at the end of each chromosome that protects the end of the chromosome from deterioration, are the genetic key to longevity.

Telomeres are repetitive DNA sequences that protect the end of the chromosome from being recognized as sites of DNA damage.

Not exact matches

Doing so keeps the telomeres found on the ends of your DNA strands long and able to protect chromosomes from deterioration.

«The whole process took about eight days,» Marks explains «and the inactivation spreads out from the centre of the X chromosome towards the ends.

Telomeres are repetitive stretches of DNA that cap natural chromosome ends to protect them from being damaged or fused together during DNA replication.

Telomere proteins from ciliated protozoa bind to the single - stranded G - rich DNA extensions at the ends of macronuclear chromosomes.

The researchers suspected that early damage from exonucleases might be going unnoticed because the uncapped ends of chromosomes fuse soon afterward.

Individuals carrying the variant had shorter telomeres, stretches of DNA at the ends of chromosomes that protect them from daily wear — and also aging

Scientists long suspected they stabilized the structure of the chromosome, preventing the tips from fraying, much like the plastic sheaths at the ends of shoelaces to prevent them from unraveling.

Telomeres are the caps at the end of chromosomes that keep them from shrinking when cells replicate.

The protein produced by this gene protects the chromosome ends of the DNA from damage, and controls telomere maintenance by the telomerase enzyme.

Biological age, Samani says, is related to the length of telomeres — stretches of DNA at the ends of chromosomes, which protect these precious packages of genes from daily wear and tear.

Research from the laboratory of Chen and his colleagues, Yinnan Chen, Joshua Podlevsky and Dhenugen Logeswaran, recently uncovered a crucial step in the telomerase catalytic cycle that limits the ability of telomerase to synthesize telomeric DNA repeats onto chromosome ends.

A molecular biologist born in Hobart, Australia, Blackburn is best known for her 2009 Nobel Prize — winning discovery of telomeres, caps on the ends of chromosomes that protect genetic information from damage and are thought to play an important role in aging and cancer.

They found that the inactivation of POT1 caused by these mutations leads to longer and potentially unprotected telomeres, regions at the end of our chromosomes that protect chromosomes from damage.

Inflammation also erodes telomeres, the «caps» at the ends of chromosomes that protect genes from degradation, which can lead to early cell death, premature aging and even cancer.

Research from other scientists at Johns Hopkins, he says, had suggested that some tumors, particularly those that affect the nervous system, have mutations in the ATRX gene, which produces proteins that appear to maintain the length of telomeres, repetitive segments of DNA on the ends of chromosomes that typically shorten each time a cell divides.

Telomeres are repetitive nucleotide sequences found at the end of chromosomes which protect them from deteriorating during the process of replication.

Scientists at King's College London have found that people who have previously suffered from acne are likely to have longer telomeres (the protective repeated nucleotides found at the end of chromosomes) in their white blood cells, meaning their cells could be better protected against aging.

Dang's team traced the clumping back to malfunctions in the enzyme telomerase, which maintains the caps at the ends of the chromosomes and keeps the chromosomes apart from one another.

Telomeres are important because they stop chromosomes from «fraying» or clumping together and «scrambling» the genetic codes they contain, performing a role similar to the plastic tips on the end of shoelaces, to which they have been likened.

In this situation, the movement of broken ends can cause pieces from different chromosomes to stick together, forming monster chromosomes that kill the cell.

Researchers at The Ohio State University examined blood from pregnant women to evaluate the length of telomeres — structures at the end of chromosomes that are used by scientists as a measure of biological (as opposed to chronological) age.

It helps to lengthen the telomeres — the proteins and DNA on the ends of chromosomes that prevent dividing chromosomes from fraying — and therefore increases the number of times a cell can divide.

Because a trisomic cell contains two copies of a chromosome from one parent and one copy of that chromosome from the other parent, one in three embryos which revert from trisomy to disomy will end up with a pair of chromosomes from just one parent.

Telomeres — repeating segments of DNA on the ends of chromosomes — are often likened to the plastic caps that prevent shoelaces from fraying.

Researchers from Leibniz Institute for Age Research — Fritz Lipmann Institute (Jena, Germany) now identified a crucial role of telomeres, the end structures of chromosomes, for sensing cells with a wrong chromosome number, referred to as aneuploidy.

Notably, the CRG team, which counted with the expertise in Mycoplasma from the Serrano's laboratory and the collaboration of the ICREA research professor Marc Marti - Renom at CNAG - CRG, discovered that Mycoplasma's circular chromosome is consistently organised the same way in all the cells, with a region called the Origin (where DNA copying begins) at one end of the structure and the midpoint of the chromosome located at the opposite end.

The study, publishing online January 18 in the American Journal of Epidemiology, found elderly women with less than 40 minutes of moderate - to - vigorous physical activity per day and who remain sedentary for more than 10 hours per day have shorter telomeres — tiny caps found on the ends of DNA strands, like the plastic tips of shoelaces, that protect chromosomes from deterioration and progressively shorten with age.

Telomeres (in white) cap the ends of human chromosomes, protecting the genetic information from damage.

There are two known cases of developmentally programmed locus - specific re-replication: Drosophila follicle cells, and salivary gland polytene chromosomes from the end of Sciara larval life.

Our lab studies various aspects of chromosome biology ranging from the maintenance of chromosome ends by telomerase to meiosis, hybridization and ploidy.

Structures at the end of chromosomes called telomeres protect cells from deterioration or fusion with other chromosomes.

Excess cortisol has been found to shorten the telomeres — the «caps» at the ends of chromosomes that prevent them from tangling with each other.

They protect chromosome ends from being mistaken for broken pieces of DNA that would otherwise be fixed by cellular repair machinery.

At the tips of each chromosome, at the end of each DNA strand, there's a cap, like the tip of a shoelace, which keeps our DNA from unraveling and fraying.

New research from a team at Karolinska University suggests that people who stand a lot have longer telomeres - caps on the end of chromosomes which protect DNA from wear and tear.