Sentences with phrase «engineered laboratory mice»

Now scientists have moved a step closer to that possibility by wiping away a month - old memory in genetically engineered laboratory mice, while leaving other memories unchanged.

Not exact matches

In laboratory tests on embryonic mice engineered to not express myomerger in skeletal muscle, the animals did not develop enough muscle fiber to live.

In this study, published in the October 31 issue of the Proceedings of the National Academy of Sciences, Sudhir Yadav PhD, a neuroimmunology post-doctoral fellow in the laboratories of Drs. Kouichi Ito, associate professor of neurology, and Suhayl Dhib - Jalbut, professor and chair of neurology, tested mice that were engineered to have a pre-disposition for MS. Because mice would not normally develop MS, researchers used MS - associated risk genes from real patients to genetically engineer mice for this study.

Most animal studies of the disease are conducted with laboratory mice that have been genetically engineered and bred to model ALS, but for this research, investigators used rats with ALS because they more accurately portray the disease's variable course in humans.

Once engineered cells are engrafted into laboratory mice, their GRN becomes even closer to that of the true target tissue, indicating that the body's own tissues contribute signals to enhance the performance of transplanted cells.

Caribou granted The Jackson Laboratory (JAX) non-exclusive, worldwide rights to use Caribou's CRISPR - Cas9 intellectual property to create genetically engineered mice for research purposes in 2016.

Gold nanotubes engineered to a specified length, modified surfaces, and to have other desirable characteristics showed expected abilities to enter tumor cells in laboratory studies, and to distribute to tissues within live mice as intended.

He was the first to engineer mice that develop the cerebral plaques and tangles that characterize Alzheimer's, providing researchers with a crucial «living laboratory» of the disease.

In the April 13, 2007, issue of Science, the research team — led by James C. Lo, an MD, PhD student, in the laboratory of Yang - Xin Fu, MD, PhD, professor of pathology at the University of Chicago — suggest that an engineered protein could keep mice, and possibly humans, from developing high cholesterol and triglyceride levels, a key risk factor for coronary heart disease.

Because he holds a dual appointment with The Jackson Laboratory, which studies mice, he is also seeking insight into how to reverse - engineer the process of regeneration in humans by comparing the genetics of the axolotl, which can regenerate, with those of the mouse, which for the most part can not.

Not so long ago, the advent of powerful genomic tools and genetic engineering techniques made it seem that studies involving mice engineered to carry human disease genes would be the best approach for exploring human disorders, superior to looking at cells isolated in a laboratory.