«If this same alternative ubiquitination process occurs in humans, perhaps
an engineered ubiquitin - editing protein could be developed to target and control processes critical to the development of many diseases, including infection,» Luo said.
To achieve this, the research team devised a system that expresses two genetically
engineered ubiquitin molecules at once.
«We are also working on
an engineered ubiquitin that targets a corn virus responsible for destroying large swaths of corn fields in North America, with colleagues in Manitoba,» says Zhang.
Not exact matches
Zhang and colleagues
engineered the human
ubiquitin protein into a new form that paralyses a key MERS enzyme, stopping the virus from replicating.