Yang's group took advantage of genetically
engineered young mice that have protein markers which glow in response to changes in nerve function.
Not exact matches
Plasma from old
mice didn't have a strong effect when injected into
young mice genetically
engineered to lack VCAM1 in certain blood - brain barrier cells.
«The dynamics of bone growth in
young mice and in children are very different from those in adults,» said Ken Kozloff, associate professor of orthopaedic surgery and biomedical
engineering.
For example,
Young's research shows normally monogamous prairie voles do not develop pair bonds with their mates if their mu - opioid system is blocked; other studies have found that
mice genetically
engineered to have no mu - opioid receptors do not prefer their mothers to other
mice the way normal baby
mice do.
The team found they could replicate the healing abilities of the
engineered mice by giving nongenetically altered ones drugs that help activate certain metabolic processes — the same pathway Lin28a stimulates — revving up and energizing cells as if they were much
younger.