Sentences with phrase «engineering human stem»

However, advancements in engineering human stem cells are now allowing researchers to grow mini-organs in labs, and gene - editing tools can be used to insert specific mutations into these cells.

To build an in vitro model of the human glomerulus to probe deeper into its function and vulnerabilities to disease and drug toxicities, researchers have been attempting to engineer human stem cells — that in theory can give rise to any mature cell type — so that they form into functional podocytes.

Not exact matches

Members interested in this area of work develop human rights ‐ related activities and services for the science, technology, engineering and mathematics (STEM) community to build the commitment and capacity of professional associations to engage meaningfully in human rights by leveraging the experience of their members.

To see whether this also applies to humans, the team engineered stem cells from people with and without Down's syndrome and injected them into mice.

On to the blocks were poured a mixture of recombinant human bone morphogenic protein (BMP) powder — a genetically engineered protein that causes cells to ossify or become bone — and liquid bone marrow containing stem cells.

Then, to boost the number of cells, which is another hurdle in tissue engineering, the researchers mixed the chondrocytes with human mesenchymal stem cells from bone marrow.

To hunt for drugs that target these cells, Piyush Gupta, a molecular biologist at the Broad Institute at the Massachusetts Institute of Technology, and colleagues genetically engineered ordinary human cells so that they acquired some of the properties of cancer stem cells, including being impervious to chemotherapy.

Innovations resulting from science, technology, engineering and mathematics (STEM) fields have positively touched nearly every aspect of human life.

To fully realize the field's clinical potential, the tissue engineers of the future must possess «a broad understanding of basic sciences (including biology, chemistry, and physics) and a sophisticated understanding of human pathophysiology, stem cell biology, and tissue mechanics.»

This event will provide an overview of the recent National Research Council report, «Successful K - 12 STEM Education,» as well as give examples of innovative research - based tools for engineering education funded by the National Science Foundation's Directorate for Education and Human Resources.

«Genetic engineering of human stem cells has not been used for disease - associated genomic deletions,» said Dr. Papapetrou.

Tufts University biomedical engineers recently published the first report of a promising new way to induce human mesenchymal stem cells (or hMSCs, which are derived from bone marrow) to differentiate into neuron - like cells: treating them with exosomes.

In fact, recent breakthroughs in the creation of human induced pluripotent stem cells (IPS) and the engineering of biodegradable scaffolds to create tissues may ultimately be applicable to most health conditions known to humankind.

Once Katlyn arrived in May 2007, Candotti and his team removed stem cells from her bone marrow and exposed them to the engineered retrovirus, creating a human - virus hybrid.

A company called Hematech is already breeding genetically engineered cattle (derived from cloned stem cells) that produce human antibodies to fight bacterial infections, and the animals» welfare is not compromised in any way.

Kotton built a reporter gene that glowed green when the stem cells first expressed Nkx2 - 1, and Hawkins engineered the same gene into human cells.

Shah and his team induced toxin resistance in human neural stem cells and subsequently engineered them to produce targeted toxins.

They used the gene editing technology CRISPR to engineer a series of human embryonic stem cell lines, which were identical apart from the number of DNA repeats that occurred at the ends of their HTT genes.

Activities supported by the Fund include the AAAS Science and Human Rights Coalition's Student Essay, Poster, and Digital Media Competitions; efforts to promote the integration of human rights into STEM education; technical training of human rights practitioners in innovative applications of science and technology; collaborative partnerships between scientists, engineers and human rights organizations; and policy engagement on issues at the nexus of science and human riHuman Rights Coalition's Student Essay, Poster, and Digital Media Competitions; efforts to promote the integration of human rights into STEM education; technical training of human rights practitioners in innovative applications of science and technology; collaborative partnerships between scientists, engineers and human rights organizations; and policy engagement on issues at the nexus of science and human rihuman rights into STEM education; technical training of human rights practitioners in innovative applications of science and technology; collaborative partnerships between scientists, engineers and human rights organizations; and policy engagement on issues at the nexus of science and human rihuman rights practitioners in innovative applications of science and technology; collaborative partnerships between scientists, engineers and human rights organizations; and policy engagement on issues at the nexus of science and human rihuman rights organizations; and policy engagement on issues at the nexus of science and human rihuman rights.

«Our group pioneered the development of cell culture technology for harvesting large numbers of stem cells from human bone marrow and human umbilical cord blood,» Dr. Yeh said, noting that stem cells from these two sources are abundant and can be guided into different types of cells using tissue engineering.

«The introduction of mitochondria into damaged cells has beneficial effects on the health of cells and, in the long term, we believe that mesenchymal stem cells could even be engineered to create more effective therapies for lung disease in humans.»

Single - cell RNA - Seq analysis also helped researchers benchmark the engineered 3D liver tissues generated from stem cells against naturally occurring human fetal and adult liver cells.

Dr. Sonntag studies this concept on the molecular and cellular level using a translational research approach that integrates the analysis of human material, such as postmortem brains, primary cell systems, and neural cell populations generated from patients» - or healthy individuals» - derived induced pluripotent stem cells (iPSC), or induced neurons (iNs), in combination with molecular, biochemistry, and lentivirus - mediated gene - engineering technologies.

INGESTEM, the national infrastructure in biology and health certified by the «Investissements d'Avenir» program and the Ile - de-France Region (DIM Biothérapies), is the first French network of therapeutic innovations based on pluripotent stem cells, human tissue engineering and their biomedical applications.

Non-virally engineered human adipose mesenchymal stem cells produce BMP4, target brain tumors, and extend survival.

Cardiac repair in guinea pigs with human engineered heart tissue from induced pluripotent stem cells.

Using human stems cells and segments of rat intestines, scientists engineer bowels that are capable of absorbing nutrients.

San Diego, CA (December 9, 2008)-- Novocell, Inc., a stem cell engineering company, today announced a collaboration with renowned stem cell researcher Dr. Shinya Yamanaka of Kyoto University, Japan, to allow Novocell to explore the creation of human islet cells from induced pluripotent stem (iPS) cells.

San Diego, CA (June 3, 2009)-- Novocell, Inc., a stem cell engineering company, today announced that it has received U.S. Patent No. 7,541,185 with method claims covering the use of endoderm cells derived from human embryonic stem cells (hESCs) for drug discovery.

The team used genetically engineered mice to study the effects of different human apoE variants on the maturation of neural stem cells or progenitor cells, from which new neurons develop in the adult brain.

ANN ARBOR, Mich — By combining engineered polymeric materials known as hydrogels with complex intestinal tissue known as organoids — made from human pluripotent stem cells — researchers have taken an important step toward creating a new technology for controlling the growth of these organoids and using them for treating wounds in the gut that can be caused by disorders such as inflammatory bowel disease (IBD).

We have recently developed the use of site - specific nucleases to genetically engineer human pluripotent stem cells, which can be maintained indefinitely and differentiated into any cell type of interest.

InvivoSciences makes engineered heart tissues from mouse embryonic stem cells and stem cells from differentiated adult tissues in humans, such as fat and skin.

The SFI Investigators Programme supports the development of world - class research capability and human capital in areas of science, technology, engineering and mathematics (STEM) that demonstrably support and underpin enterprise competitiveness and societal development in Ireland.

Gladstone scientists are engineering tissues from stem cells to create better models of human disease.

Zonari E, Desantis G, Petrillo C, Boccalatte FE, Lidonnici MR, Kajaste - Rudnitski A, Aiuti A, Ferrari G, Naldini L, Gentner B. Efficient ex vivo engineering and expansion of highly purified human hematopoietic stem and progenitor cell populations for gene therapy.

Embryonic stem cells derived from human blastocysts have the key advantage of pluripotency, meaning that they form nearly all cell types but also have the disadvantage of forming tumors in vivo, which may limit clinical application to tissue engineering rather than cell transplantation.

San Diego, CA (March 31, 2009)-- Novocell, Inc., a stem cell engineering company, today announced that it has received U.S. Patent 7,510,876 with claims covering human definitive endoderm cells, an essential cell for generating not only pancreatic type cells, which Novocell is developing for use as a cell therapy for diabetes, but also other endoderm lineage - derived tissues and organs such as lungs, intestine, liver, thymus and thyroid.

Gladstone's newest recruit, Dr. McDevitt, will continue to use his background in biomedical engineering to improve and accelerate the development of human tissues from stem cells.

McDevitt, a senior investigator at Gladstone, received the award to fund his efforts to use human pluripotent stem cells to engineer microscale tissue constructs.

There is evidence that computer - based tutoring can yield results similar to one - on - one tutoring in certain subjects, such as science, technology, engineering, and math (STEM) fields, 27 or when certain principles of the cognitive science of learning — such as self - explanation — are embedded in the program or software.28 While these programs can not replace the need for human interaction and relationships, they may be effective for some students and allow for greater targeting of resources toward students who most need traditional one - on - one tutoring.

Distilling the most radical accomplishments being made in labs worldwide, including gene therapy, genetic engineering, stem cell research, life extension, brain - computer interfaces, and cloning, More Than Human offers an exciting tour of the impact biotechnology will have on our lives.

The White House, in partnership with the U.S. Departments of Education and Health and Human Services and Invest in US, hosted a symposium last week to highlight the importance of promoting active science, technology, engineering, and math (STEM) learning for our youngest children.