Genetic
engineering of human antibodies; host defense mechanisms against microbial infection.
Not exact matches
That's why researchers are
engineering plants to produce key parts
of viruses and bacteria, in the hope that the
human body will take them for invaders and start producing
antibodies against the organisms.
The company now has an array
of fully
human antibodies in its pipeline created with its proprietary VelocImmune mouse, which has been
engineered to express
human antibody genes while still mounting a robust immune response by making
antibodies with fully
human variable regions and mouse constant regions.
An
antibody engineered to prevent excessive bleeding in patients with severe hemophilia A may be safe and effective, and require fewer injections than existing options, according to a first - in -
human study
of the treatment published online today in Blood, the Journal
of the American Society
of Hematology (ASH).
This research involved the use
of specially bred «transchromosomal» cows that have been
engineered to produce fully
human antibodies.
The breakthrough arrived in the form
of genetically
engineered mice that, thanks to inserted
human genes, made
antibodies that were fully
human.