Sentences with phrase «engineering specific sequence»
Not exact matches
Moreover, the ability to easily program sequence - specific DNA targeting and cleavage by CRISPR - Cas components, as demonstrated for Cas9 and Cpf1, allows for the application of CRISPR - Cas components as highly effective tools for genetic engineering and gene regulation in a wide range of eukaryotes and prokaryotes.
http://science.sciencemag.org/
Protein - based targeting strategies rely on custom - engineered modular proteins that recognize and bind to specific DNA sequences.
In a study featured in the journal Science, Dr. Feng Zhang and his colleagues at the Broad Institute at MIT described how they were able to engineer the C2c2 enzyme in order to search out and break apart specific RNA chemical sequences.