Sentences with phrase «engraftment with human cells»
We have developed SCID mouse models that support high levels of engraftment with human cells and tissues to overcome these limitations.
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We have collaborated nationally and internationally with colleagues to develop improved humanized mouse models and optimize the technologies used for engraftment of normal and malignant human cells and tissues.
Eight weeks postinjection, the engraftment was confirmed by flow cytometric staining of peripheral blood cells for human CD45 + / CD33 + cells, followed by randomization into study groups and treatment with a single bolus IV injection of IMGN632 or the control ADC.