This increase in NAD levels is far superior compared with the 2-fold increases generally observed in most genetic (PARP - 1 deletion), pharmacological (NAD precursors), or physiological interventions (fasting, calorie restriction) that
enhance NAD content.
Not exact matches
«Finding out whether strategies to
enhance the production of
NAD will have any impact on muscle function in healthy individuals is a subject of much speculation,» Baur said.
These findings suggest that the efficacy of
NAD + precursors may be
enhanced by co-supplementation with CD38 inhibitors
Brain tissue is highly sensitive to alterations in
NAD + levels.67 A mouse study showed that supplementation with nicotinamide mononucleotide increased
NAD + levels in the brain, slowed cognitive decline in mice with Alzheimer's, and
enhanced the plasticity in neurons that underlies learning and memory.67