Sentences with phrase «enhanced cell survival»

These physical effects lead to cell signaling pathways for enhanced cell survival.

The results were that BES enhanced cell survival and prevented the apoptosis of NPCs caused by growth factor deprivation.

Loss of PTPN12 Stimulates Progression of ErbB2 - Dependent Breast Cancer by Enhancing Cell Survival, Migration, and Epithelial - to - Mesenchymal Transition.

Not exact matches

A Canadian study published this year around the same time titled «Coconut oil protects cortical neurons from amyloid beta toxicity by enhancing signaling of cell survival pathways» observed that coconut oil and its medium chain fatty acids (MCFAs) protect against amyloid beta (Aβ) induced neurotoxicity in primary rat cortical neurons.

«In animal studies, exercise has been shown to specifically affect the hippocampus, significantly increasing the growth of new neurons and cell survival, enhancing memory and learning, and increasing molecules that are involved in the plasticity of the brain,» Chaddock said.

When optimal temperatures are restored, the plant stem cells can divide at a faster rate, which will in turn enhance recovery and survival of the plant.»

In order to learn more about how celecoxib was enhancing stem cell survival and wound healing, the researchers conducted experiments to identify the cytokines or enzymes directly or indirectly influencing the process.

The research team, spearheaded by postdoctoral fellow Yajie Liang, Ph.D., wondered whether the cells» survival could also be enhanced with steady doses of a compound called basic fibroblast growth factor (bFGF), an «energy drink» that spurs cells to grow.

The transcription factor Runx3 enhances the differentiation and survival of CD8 + resident memory T cells; enhancing Runx3 expression in responding T cells could lead to better therapies for infection and cancer.

The mechanism for this markedly enhanced effect appears to be increased cell survival and retention.

Importantly, while the enhanced presence of Bcl - xL is expected to promote cancer cell survival in the first place, it may also indicate that the apoptotic machinery (especially the caspases) are still in place, making it necessary for the tumor cell to maintain a high level of Bcl - xL [10].

Researchers have discovered that inducing quiescence in stem cells may be an effective means to enhance stem cell survival

Strikingly, this cancer cell subpopulation displayed enhanced expression of Bcl - xL, strongly suggesting that the upregulation of this antiapoptotic protein also supports the survival of invasive cancer cells within patients.

Moreover, the proapoptotic gene products BBC3 / Puma and BCL2L11 / Bim were downregulated in mesenchymal cells, possibly contributing further to their enhanced survival.

• Keeping abnormal proteins from building up and potentially shutting down major organs (heart, liver and nervous system, to name a few) • Protecting the brain's functions of learning and memory against neurotransmitter toxicity • Activating or increasing the activity of proteins that promote the initial growth, maintenance and survival of brain neurons • Enhancing the movement of proteins, lipids and other cell parts through the cytoplasm of cell bodies.

ORAI1 Deficiency Impairs Activated T Cell Death and Enhances T Cell Survival.

Direct Transcriptional Up - regulation of Cyclooxygenase - 2 by Hypoxia - Inducible Factor (HIF)-1 Promotes Colorectal Tumor Cell Survival and Enhances HIF - 1 Transcriptional Activity during Hypoxia

Thus apart from direct cytotoxic effect, the exposure of cancer cells to therapeutic doses of radiation also enhances the survival and proliferation of a fraction of cells which ultimately leads to radiation resistance and therapeutic inefficacy.

Significant advancements have been made in the bioprocessing of hPS cells including the formulation of new cell culture media, the development of extracellular and acellular matrices that can replace feeder cells, the development of new enzymes for passaging and the discovery of small molecules that significantly enhance the survival and clonogenicity of dissociated cells, allowing single cell cryopreservation.

Vignali and his colleagues used a variety of molecular and cellular techniques to show that Sema4a binding to Nrp1 turns on a biochemical pathway in mouse regulatory T cells that enhances their function, stability and survival.

We then evaluated whether the encapsulation of hPSC - CDH5 + cells in PA - RGDS could enhance long - term cell survival and vascular regenerative effects in a hind - limb ischemia model with laser Doppler perfusion imaging, bioluminescence imaging, real - time reverse transcription - polymerase chain reaction, and histological analysis.

In breast cancer cells, the ABL kinases activated the transcriptional coactivator TAZ and the transcription factor STAT5, which triggered the transcription of genes encoding factors that activate osteoclasts (cells that break down bone) and those that enhance the survival of breast cancer cells in the bone microenvironment.