The researchers next investigated whether ultrasound -
enhanced drug delivery could effectively treat disease in animals.
The researchers have coated DNA nanostructures with virus capsid proteins in order to significantly improve their transport to human cells; this could find uses for example in
enhanced drug delivery.
Langer began exploring the possibility of using ultrasound to
enhance drug delivery 30 years ago.
Not exact matches
Dry powder inhalers exhibit several advantages over traditional
drug delivery methods, including improved formulation stability,
enhanced delivery efficiency, excellent portability and ease of use.
While on one hand, there is significant potential in the application of nanoparticles in
enhancing heat transfer for tumor ablation and targeted
drug delivery, there is also much promise in improving imaging and diagnostic protocols using them.
Nanoparticles are ubiquitous in industrial applications ranging from
drug delivery and biomedical diagnostics to developing hydrophobic surfaces, lubricant additives and
enhanced oil recovery solutions in petroleum fields.
We are particularly interested in leverage our interdisciplinary expertise in polymer chemistry, nanomedicine,
drug delivery and immunobiology to innovate new approaches to modulate the tumor microenvironment and
enhance cellular immune responses to cancer vaccines.
Microvesicle - and exosome - mediated
drug delivery enhances the cytotoxicity of Paclitaxel in autologous prostate cancer cells.
Our therapeutic siRNA molecules are combined with
delivery systems, which markedly
enhance the efficiency and specificity of our siRNA
drugs by directing them to the right cell type in the body and sparing healthy tissues.
Langmuir 29 (35), 10973 - 10979 (2013) «Reduced limbic metabolism and fronto - cortical volume in rats vulnerable to alcohol addiction» A. Gozzi, F. Agosta, M. Massi, R. Ciccocioppo, and A. Bifone NeuroImage 69, 112 - 119 (2013) «Polymeric nanocarriers for controlled and
enhanced delivery of therapeutic agents to the CNS» M. Gagliardi, G. Bardi and A. Bifone Theraputic Delivery, 3 (7), 875 — 887 (2012), doi: 10.4155 / TDE.12.55 «Neuromapping techniques in drug discovery: pharmacological MRI for the assessment of novel antipsychotics» A. Bifone and A. Gozzi Expert Opinions in Drug Discovery, 7 (11): 1071 - 82 (2012) «Neuroimaging evidence of altered fronto - cortical and striatal function after prolonged self - administration in the ra
delivery of therapeutic agents to the CNS» M. Gagliardi, G. Bardi and A. Bifone Theraputic
Delivery, 3 (7), 875 — 887 (2012), doi: 10.4155 / TDE.12.55 «Neuromapping techniques in drug discovery: pharmacological MRI for the assessment of novel antipsychotics» A. Bifone and A. Gozzi Expert Opinions in Drug Discovery, 7 (11): 1071 - 82 (2012) «Neuroimaging evidence of altered fronto - cortical and striatal function after prolonged self - administration in the ra
Delivery, 3 (7), 875 — 887 (2012), doi: 10.4155 / TDE.12.55 «Neuromapping techniques in
drug discovery: pharmacological MRI for the assessment of novel antipsychotics» A. Bifone and A. Gozzi Expert Opinions in Drug Discovery, 7 (11): 1071 - 82 (2012) «Neuroimaging evidence of altered fronto - cortical and striatal function after prolonged self - administration in the rat&ra
drug discovery: pharmacological MRI for the assessment of novel antipsychotics» A. Bifone and A. Gozzi Expert Opinions in
Drug Discovery, 7 (11): 1071 - 82 (2012) «Neuroimaging evidence of altered fronto - cortical and striatal function after prolonged self - administration in the rat&ra
Drug Discovery, 7 (11): 1071 - 82 (2012) «Neuroimaging evidence of altered fronto - cortical and striatal function after prolonged self - administration in the rat»
This, coupled with the simultaneous
delivery of specific anticancer
drugs, could
enhance the therapeutic effects of such
drugs.
Ophthalmic Injection System Designed to
Enhance Safety, Reduce Malpractice and Increase Precision of
Drug Delivery for the Treatment of Eye Diseases LIVINGSTON, NJ --(Marketwired - September 22, 2014)- Milestone Scientific Inc. (OTCQB: MLSS), a...
Professional Duties & Responsibilities Biomedical and biotechnology engineer with background in design of biomaterials, biosensors,
drug delivery devices, microfrabrication, and tissue engineering Working knowledge of direct cell writing and rapid prototyping Experience fabricating nanocomposite hydrogel scaffolds Proficient in material analysis, mechanical, biochemical, and morphological testing of synthetic and biological materials Extensive experience in bio-imaging processes and procedures Specialized in mammalian, microbial, and viral cell culture Working knowledge of lab techniques and instruments including electrophoresis, chromatography, microscopy, spectroscopy, PCR, Flow cytometery, protein assay, DNA isolation techniques, polymer synthesis and characterization, and synthetic fiber production Developed strong knowledge of FDA, GLP, GMP, GCP, and GDP regulatory requirements Created biocompatible photocurable hydrogels for cell immobilization Formulated cell friendly prepolymer formulation Performed surface modification of nano - particle fillers to
enhance their biocompatibility Evaluated cell and biomaterial interaction, cell growth, and proliferation Designed bench - top experiments and protocols to simulate in vivo situations Designed hydrogel based microfluidic prototypes for cell entrapment and cell culture utilizing computer - aided robotic dispenser Determined various mechanical, morphological, and transport properties of photocured hydrogels using Instron, FTIR, EDX, X-ray diffraction, DSC, TGA, and DMA Assessed biocompatibility of hydrogels and physiology of entrapped cells Evaluated intracellular and extracellular reactions of entrapped cells on spatial and temporal scales using optical, confocal, fluorescence, atomic force, and scanning electron microscopies Designed various biochemical assays Developed thermosensitive PET membranes for transdermal
drug delivery application using Gamma radiation induced graft co-polymerization of N - isopropyl acylamide and Acrylic acid Characterized grafted co-polymer using various polymer characterization techniques Manipulated lower critical solution temperature of grafted thermosensitive co-polymer Loaded antibiotic on grafted co-polymer and determined
drug release profile with temperature Determined biomechanical and biochemical properties of biological gels isolated from marine organisms Analyzed morphological and mechanical properties of metal coated yarns using SEM and Instron Performed analytical work on pharmaceutical formulations using gas and high performance liquid chromatography Performed market research and analysis for medical textile company Developed and implement comprehensive marketing and sales campaign