With Dr. Barreiro's team, they aimed to dissect the genomic pathways involved in triggering
the enhanced innate immune response against TB.
In addition to drugs and gene constructs, there's another strategy in the works for eliminating senescent cells:
enhancing the innate immune system's ability to purge them.
Not exact matches
The researchers found glucocorticoids tightly control bacteria - induced
innate immune and inflammatory response by
enhancing IRAK - M, one of the most critical negative feedback regulators of inflammation that inhibits the activation of the proteins MyD88 and IRAK1 / 4.
ATP hydrolysis
enhances RNA recognition and antiviral signal transduction by the
innate immune sensor, laboratory of genetics and physiology 2 (LGP2).
From this perspective, social adversity and perceived threat in childhood should upregulate the
innate immune system, a system that provides immediate defense against infection, and
enhance pro-inflammatory response tendencies as a way to prepare for potential impending tissue damage and infection.