Sentences with phrase «enhanced tumor rejection»

We observed enhanced tumor rejection in DGKζ - deficient mice and DKO mice relative to WT or Cbl - b — deficient mice.

The decreased tumor size and enhanced tumor rejection in DGKζ - deficient mice indirectly suggests that enhanced Erk signaling may be superior to enhanced NF - κΒ activation in facilitating T cell activity against tumor, especially because DKO mice did not exhibit improved tumor control relative to DGKζ − / − mice.