Sentences with phrase «enhances cancer cell invasion»

Not exact matches

The U of G researchers found that it is precisely under conditions of low oxygen that cancer cells trigger the production of cadherin - 22, putting in motion a kind of protein boost that helps bind cells together, enhancing cellular movement, invasion and likely metastasis.

Through its various targets, MMP1 promotes not only tumor invasion but also breast cancer colonization to bone by mechanisms that include the release of membrane - bound EGF - like growth factors from tumor cells, leading to activation of EGF receptor signaling and suppression of OPG expression in osteoblasts, which in turn promotes the differentiation and activation of osteoclasts required for bone destruction and enhanced tumor growth in the bone microenvironment (32).

Epithelial - mesenchymal transition (EMT) contributes to the progression of cancer through enhanced invasion and stem - like properties of cancer cells.

Multiple studies have shown that fascin, through its role in formation of cellular protrusions such as filopodia and invadopodia, enhances cancer cell migration and invasion in vitro.