Sentences with phrase «enriching cell populations»

A couple of other research groups have also sorted stem cells based on gene expression, but they have not done so specifically with the goal of enriching cell populations for a specific tissue, the researchers said.

Perigonadal adipose tissue was collected from female B6.V Lepob / ob mice, digested, and centrifuged to yield a buoyant adipocyte - enriched cell population (gray bars) and a pellet of SVCs.

Carcinoma - associated fibroblasts (CAFs) are a highly enriched cell population in the tumor microenvironment that plays an important role in cancer invasion.

Not exact matches

«Umbilical cord blood contains an enriched population of bone marrow stem cells,» says Daniel Weisdorf, director of the Adult Blood and Marrow Transplant Program at the university.

«In combination with recent advances in sorting cells on a biophysical basis, the biomechanical stemness markers we identified hold the potential to rapidly generate corneal transplants with highly enriched stem cell populations, which could one day translate into better outcomes for these patients.»

The adipocyte - enriched population (gray bars) expressed small amounts of the macrophage markers (a), consistent with residual macrophage contamination seen by immunofluorescent staining of live cells (b).

To determine whether adipose tissue macrophages express any molecules implicated in obesity - associated complications, we isolated three cell populations from the parametrial adipose tissue of three obese B6.V Lepob / ob mice: (a) an adipocyte - enriched population, (b) a stromal vascular macrophage F4 / 80 + population, and (c) an F4 / 80 — stromal vascular population.

Enriched population of PNS neurons derived from human embryonic stem cells as a platform for studying peripheral neuropathies.

This led researchers from the group of Joseph S. Anderson (University of California Davis, USA) to formulate a new strategy; the use of a combined anti-HIV and selection vector [5, 6] to enrich for modified HSPCs, to provide a pure and effective cell population for therapeutic purposes.

No significant differences were seen between the normoxic and hypoxic anoikis - resistant populations collected from MCF7 cells and a single significant gene change (PIP) was seen in T47D (Table 1) suggesting that the CSC - enriched population remains virtually unchanged following hypoxic culture and the increase in MFC, HFC, and tumor initiating cells is, therefore, due to expansion of the population, perhaps by increased symmetric self - renewal of the CSC or de-differentiation of early progenitor cells, rather than simply the acquisition of anoikis resistance in non-CSC.

CSC enrichment was achieved by collection of anoikis - resistant cells as we have previously shown this population to be highly enriched for mammosphere and tumor - initiating cells (25).

Our previous work has shown that the CD44 + and CD44 + α2β1 + prostate cancer cell populations are enriched in tumorigenic and metastatic CSCs, whereas the α2β1 + prostate cancer cells most likely mark fast - proliferating tumor progenitors (28, 29).