Sentences with phrase «entire chromosome»

By carefully tracing the genome as it folds, the team found that they could stitch together hundreds of millions of short DNA reads into the sequences of entire chromosomes.

Almost all cancer cells have gained or lost entire chromosomes.

The fused gene in turn produces abnormal proteins that destabilize entire chromosomes, resulting in aggressive cancers.

The role of aneuploidy — in which entire chromosomes or chromosome arms are added or deleted — has remained largely unstudied.

According to the researchers, the interplay between the two proteins is necessary for the flawless and smooth repair of crosslink damage as it prevents the relocation of entire chromosome sections to another position (see figure).

Copy number variations of entire chromosomes underlie well - known developmental disorders such as trisomy 21, or Down's syndrome.

But damage to an entire chromosome, he says, is like removing an entire section of an assembly line and plunking it down where it shouldn't be.

Last spring Daniel Cohen, the dynamic scientist behind Genethon's robots, hit the headlines when he announced that his team had already mapped 28 per cent of the human genome, including most of one entire chromosome.

«Inbreeding has been so extensive that some individuals have entire chromosomes that completely lack genetic variation», says Hans Ellegren, Professor at the Evolutionary Biology Centre, Uppsala University and leader of the study.

In recent years, research has shown that genomic complexity «happens» in many ways, including duplication and deletion of genes, cascades of genes, and, in complex organisms, entire chromosomes can be affected.

Researchers analyzing the machinery the roundworm C. elegans uses to repress genes on an entire chromosome have found surprising principles that may apply widely to this type of wholesale gene...

All are triggered by simple deletions or substitutions of one DNA base — unlike Down's syndrome, which is caused by the doubling of an entire chromosome and is usually inherited from the mother.