Sentences with phrase «entire coding sequence»

Molecular evolutionary analysis of the entire coding sequence in the eight representative mammalian species: Monotremes (platypus), Marsupials (opossum) and Eutherians (mouse, rat, dog, rhesus monkey, chimpanzee and human), revealed no excessive non-synonymous nucleotide changes in comparison with synonymous changes.

Not exact matches

They sequenced the entire nuclear genome of this species, and identified all of the genes within that genome that code for biological functions.

His automated genome - sequencing machine is driving the price of mapping a person's entire genetic code down toward $ 1,000, almost unbelievably cheap considering that, less than a decade ago, the government - funded Human Genome Project spent roughly $ 3 billion to sequence a single genome.

The third is a method implemented by Reich for reading the genetic codes of 1.2 million carefully chosen variable parts of DNA (known as single nucleotide polymorphisms) rather than having to sequence entire genomes.

In a few years prenatal whole - genome sequencing will provide the entire genetic code of an unborn fetus, alerting parents of possible genetic diseases their child may have or develop.

The human genome contains about 3 billion base pairs, but only about 2 percent of these base pairs represent protein - coding genes, meaning that whole - exome sequencing measures the genetic alterations focused on a small but very important fraction of the genome (as opposed to techniques of whole genome sequencing, which measures every nucleotide across the entire genome, regardless of whether these genes are expressed or silent).

1994 - 1996 — Collins» focus shifts to sequencing the entire human genetic code at NIH.

The researchers discovered the foreign DNA sequences of Agrobacterium while searching the genome — this is the entire DNA - code — of sweet potato for viral diseases.

The branch uniting the fungi and animals is well - supported based on a number of molecular phylogenetic datasets, including the nuclear small subunit ribosomal RNA gene (Wainwright et al., 1993; Bruns et al. 1993), unique and shared sequence insertions in proteins such as elongation factor 1α (Baldauf and Palmer, 1993), entire mitochondrial genomes (Lang et al., 2002), and concatenated protein - coding genes (Steenkamp et al., 2006).

Should you cut it at the beginning of the coding sequence to delete the entire gene?

To reveal the structural genetic code, researchers examine chromatin from its sequence of nucleotides to the organisation of an entire genome.

The DNA we can retrieve from passenger pigeon specimens is too fragmented to reassemble the entire genomic code — but we can map the sequence of genes and gene regulating regions that are most important to creating passenger pigeon traits.

Genomic sequencing of the isolated virus revealed that it is closely related to Tembusu virus (a mosquito - borne Ntaya group flavivirus), with 87 — 91 % nucleotide identity of the partial E (envelope) proteins to that of Tembusu virus and 72 % of the entire genome coding sequence with Bagaza virus, the most closely related flavivirus with an entirely sequenced genome.

For this purpose, we established a transgenic fly line that carries an ~ 80 - kb genomic region containing the entire CCHa2 - R coding region, as well as substantial flanking sequence.

We performed pair-wise comparison of Ka and Ks for the entire boule coding sequences among seven Drosophila species (Dmel - D.

We compared the entire boule coding sequences among seven Drosophila species (D. melanogaster, D. sechellia, D. yakuba, D. virilis, D. erecta, D. willistoni and D. ananassae) as well as eight representative mammalian species [56].

The researchers then analyzed another 147 colorectal cancer cell lines in the same way for kinase - domain mutations in these genes, and then sequenced the entire coding region of all kinases that were mutated, in all discovering 46 new mutations.

DNA sequencing is also used to assess our planet's health and to break genomic codes of entire ecosystems.

This will include robotic DNA extraction, genome - wide mapping with high density gene chips (querying 175,000 DNA markers), and next - gen sequencing of the entire genome of an affected dog (interrogating every letter of the 2.4 billion letter genetic code).

The DNA we can retrieve from passenger pigeon specimens is too fragmented to reassemble the entire genomic code — but we can map the sequence of genes and gene regulating regions that are most important to creating passenger pigeon traits.