Sentences with phrase «enucleated egg cell»

The procedure transplants nuclear DNA from an egg of a woman with mitochondrial disease into an enucleated egg cell from a woman with healthy mitochondria.
SCNT is a technique wherein the nucleus from a somatic cell (an adult cell that is not a sperm or egg, i.e. not the gametes) is implanted into an enucleated egg cell which can then be implanted into, and develop in, a surrogate mother, and potentially become an adult organism.
The next steps in cloning would be to 1) insert a donor nucleus of a new bird into the enucleated egg cell, 2) stimulate embryonic growth, and 3) implant the embryo into a mother bird or egg.
But the next step — transferring the nucleus — was different; rather than fusing the donor cell with the enucleated egg cell, the team removed the donor nucleus with a very fine needle and injected it into the donor egg.
The only way to do this now is by nuclear transfer to an enucleated egg cell («therapeutic cloning»).
OAR proponents claim that when the altered donor - cell nucleus with its activated nanog gene is transferred to the enucleated oocyte (egg cell), the presence of nanog will immediately convert the enucleated egg cell to a pluripotent cell, without ever forming a zygote.
The resulting cells are themselves fused with other enucleated egg cells.
A team in the laboratory of Atsuo Ogura at the National Institute of Infectious Diseases in Shinjuku, Tokyo, cloned 12 mice by removing nuclei from testis cells and inserting them into enucleated egg cells.

Not exact matches

Then, the DNA would be removed from an oocyte (an egg cell) and this enucleated oocyte fused to the altered adult cell» creating a new cell that is neither an oocyte nor an adult cell but a hybrid exhibiting the properties programmed into it by the alterations made to the adult - cell nucleus.
Other researchers have previously cloned animals, including mammals, by transferring nuclei from embryonic cells into such enucleated eggs.
He tested various methods to quickly and precisely remove the nuclear materials from the egg cell and promote the fusion of the nucleus - donor cell and enucleated egg.
After many attempts, CC was created by coaxing the nucleus of a cell from a calico cat into an enucleated egg; an electrical spark prompted the hybrid to divide, and the resulting embryo was then transferred into a surrogate mother.
You take that cell and fuse it to the enucleated egg, activate it — which starts it growing — and transfer it to a surrogate mother.
Wilmut and his colleagues transplanted a nucleus from a mammary gland cell of a Finn Dorsett sheep into the enucleated egg of a Scottish blackface ewe.
In 1996 researchers in Scotland used SCNT to transplant the nucleus of an adult sheep cell into an enucleated sheep egg, producing Dolly, the first cloned mammal.
In essence, these studies suggested that a newly fertilized, enucleated egg has the ability to «reprogram» a much older donor nucleus, making the resultant cell behave as though it were at a very early embryonic state.
SCNT is a technique wherein the nucleus from a somatic cell (an adult cell that is not a sperm or an egg) is implanted into an enucleated egg which can be implanted into, and develop, in a surrogate mother, and potentially become an adult organism.
In 1938, Hans Spemann showed that a nucleus from a fertilized salamander egg that had already undergone cell division several times could be implanted into a cell from a newly fertilized salamander egg that is enucleated (has had its nucleus removed) and create an entire adult salamander (Spemann, 1938).
An adult cell from the mammary gland of a Finn - Dorset ewe acted as the nuclear donor; it was fused with an enucleated egg from a Scottish Blackface ewe, which acted as the cytoplasmic (or egg) donor.
This theoretical feat involved two key components: (1) a fertilized egg that has had its nucleus removed (what is called «enucleated»), and (2) a nucleus from an older cell.
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