«More detailed information may make it possible to better understand where the bacteria came from — from what sort of animal, or from what part of the world,» explains Robert Tauxe, deputy director of foodborne, waterborne and
environmental diseases at the CDC.
Not exact matches
Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of
diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or
at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and
environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.
Still, looking
at someone's genome alone will probably never be enough to determine if they'll go on to develop a psychiatric
disease — other factors, including
environmental factors like severe stress, play a strong role too.
«Consumers should be as concerned as the foremost infectious
disease doctors are — which is very concerned,» David Wallinga, a senior health officer
at the
environmental nonprofit the National Resources Defense Council, who contributed to the report, told Time.
«We advise families with private wells to have their tap water tested for arsenic,» Dr. Margaret Karagas, senior author and professor
at Dartmouth's Children's
Environmental Health and
Disease Prevention Research Center, said in a press release.
«I urge the National Center for
Environmental Health and the Agency for Toxic Substances and
Disease Registry to work with their partners
at the New York State Department of Health to offer blood testing to residents of Newburgh, so that they can finally begin to have clarity about the extent of this problem,» she said.
Also
at 12:30 p.m.,
environmental advocate Erin Brockovich, the Alliance to Prevent Legionnaires»
Disease, and the Allergy and Asthma Network will hold a press conference to call on lawmakers and health officials to work towards real, effective solutions to New York's escalating Legionella and Legionnaires» disease crises, LOB, Room 130, 198 State St.,
Disease, and the Allergy and Asthma Network will hold a press conference to call on lawmakers and health officials to work towards real, effective solutions to New York's escalating Legionella and Legionnaires»
disease crises, LOB, Room 130, 198 State St.,
disease crises, LOB, Room 130, 198 State St., Albany.
In addition, Belinda has many hours of graduate work
at the Tulane School of Public Health & Tropical Medicine, with a specialization in International Health, Infectious
Disease Control and
Environmental Health.
Travis Book, an
environmental group manager
at Barclay Water Management, said it is fairly common for cooling towers to become reinfected with Legionella, the bacteria that causes Legionnaires»
disease, even after being cleaned for it, given how ubiquitous it is.
Janet Stout, director of Special Pathogens Laboratory in Pittsburgh and an associate professor of research
at the School of Civil and
Environmental Engineering
at the University of Pittsburgh, has studied Legionnaires»
disease for 30 years and called the idea of legislation from the state and the pending City Council legislation «unprecedented.»
«Our findings suggest that teens and young adults who seek indoor tanning may be especially vulnerable to developing BCC, the most common form of skin cancer,
at a young age,» said lead author Professor Margaret Karagas, co-director of the Cancer Epidemiology and Chemopreventon Research Program
at the Norris Cotton Cancer Center and Director of the Children's
Environmental Health and
Disease Prevention Research Center
at Dartmouth.
They found that banned chemicals, such as pesticides that have been linked with Parkinson's
disease, have been pouring into the lake
at an increasing rate since the 1990s (
Environmental Science & Technology, DOI: 10.1021 / es901628x).
Look
at the enormous cost of
diseases of
environmental origin in children — which we've calculated
at about $ 55 billion each year for the 4 million babies born in this country.
Environmental groups and many ecologists say the ministry's cure is far worse than the
disease, and that nothing less than the future of Europe's last ancient wilderness is
at stake.
In the future, some may find work
at research institutions,
disease - focused foundations, and
environmental nonprofits, Irion says.
«The system could also be adapted for use with other respiratory viruses, and with some modification, for infectious
diseases more broadly,» says lead author Sen Pei, a postdoctoral scientist in
Environmental Health Sciences
at Columbia's Mailman School of Public Health.
This can result in a serious genetic
disease that can cause anemia, neuro - cognitive impairment, and even early death,» says the study's lead - author, Dr. Jean - Louis Guéant, director of the Inserm unit of Nutrition - Genetics -
Environmental Risks
at University of Lorraine and head of the Department of Molecular Medicine and Personalized Therapeutics — National Center of Inborn Errors of Metabolism
at the University Regional Hospital of Nancy.
Because
environmental exposures have not had time to impact IBD progression in children, researchers have a clearer genetic picture of the
disease allowing them to pick out additional genes overlooked in adult research, says senior study author Hakon Hakonarson, director of the Center for Applied Genomics
at The Children's Hospital of Philadelphia.
Trump's draconian budget request — which suggested drastic cuts to the US
Environmental Protection Agency (EPA) and the US Centers for
Disease Control and Prevention (CDC), among others — was rejected by Congress, and a spending bill that increases funding for science
at many federal agencies was signed into law.
That might sound like a good deal to all kinds of American researchers and foreign scientists currently working in the U.S. in light of massive looming Trump budget cuts
at the National Institutes of Health, the Centers for
Disease Control and Prevention, the Food and Drug Administration, the National Science Foundation, NASA, the Department of Energy, the National Oceanic and Atmospheric Administration, the U.S. Geological Survey and, of course, the
Environmental Protection Agency.
The study's lead author, Patricia Lopes from the Department of Evolutionary Biology and
Environmental Studies
at the University of Zurich, says that previous research in wild animals has generally ignored how this change in behaviour may affect social contacts in a group and how, in turn, these changes can impact the transmission of a
disease.
Co-author Dr Benedikt Schmidt, from the Institute of Evolutionary Biology and
Environmental Studies
at the University of Zurich and KARCH, the Swiss Amphibian and Reptile Conservation Programme, said: «This study has shown the threat of importing exotic species without appropriate screening for infectious
diseases.
Although it's still unknown exactly why DHA is able to prevent the onset of lupus, the researchers said this study provides scientists with a better model for looking
at just how much DHA is needed to ward off the
environmental trigger of the
disease.
The new finding is the latest evidence supporting a growing precision medicine model of psychiatric
disease in which disruptions of certain genes during brain development contribute to a person's risk for multiple psychiatric disorders, with other genetic or epigenetic drivers, random developmental events, or
environmental influences determining the specific
disease an individual develops, said senior author Benjamin Cheyette, MD, PhD, an associate professor of psychiatry and a member of the UCSF Weill Institute for Neurosciences and the Kavli Institute for Fundamental Neuroscience
at UCSF.
While genetics play a role in the development of Lupus, a systemic autoimmune
disease that can attack any organ system in the human body, so do
environmental triggers, such as particulates in air pollution and ultraviolet light, explains Gaurav Gulati, MD, a physician - researcher
at the University of Cincinnati (UC) College of Medicine.
But a large survey of identical and fraternal twins, published in July, offers convincing evidence that
environmental factors are
at least as crucial as genetics in determining whether a child will develop the neuropsychiatric
disease.
In addition, she sends some of the venom she purchases — which, due to the cost of the no - harm extraction method she uses, she says is «more expensive than gold» — to Eva Sapi, Associate Professor of Biology and
Environmental Science
at the University of New Haven, who studies Lyme
disease.
The use of statins may not be associated with lowering risk for Parkinson's
disease, according to a new study led by researchers
at Penn State College of Medicine and National Institute of
Environmental Health Sciences.
Because most cases of Parkinson's
disease appear to be
at least partially caused by
environmental factors such as pesticide exposure, these findings support the approach that targeting α - synuclein could slow or stop the progression of Parkinson's in most people with the
disease, said study lead author Jeff Bronstein, a professor of neurology and director of movement disorders
at the David Geffen School of Medicine
at UCLA.
«Crop protection products such as fungicides help farmers grow quality crops free of
disease and achieve better yields, which keeps prices low for consumers,» said Mike Leggett, senior director of
environmental policy
at CropLife America.
Through a few clever molecular hacks, researchers
at Columbia University Medical Center have converted a natural bacterial immune system into a microscopic data recorder, laying the groundwork for a new class of technologies that use bacterial cells for everything from
disease diagnosis to
environmental monitoring.
Following the largest Ebola epidemic in history last year, which claimed the lives of more than 11,000 people in West Africa and ultimately spread to the U.S., public health officials remain concerned about healthcare workers contracting Ebola or other emerging infectious
diseases such as SARS and pandemic influenza, says Rachael Jones, UIC associate professor of
environmental and occupational and health sciences, one of four co-investigators
at UIC.
That's a good thing, says Mark Keim, associate director for science in the Office of
Environmental Health Emergencies
at the U.S. Centers for
Disease Control and Prevention (CDC), it can both improve disaster response and allow affected populations to take control of their situation as well as feel empowered.
Last August, a 27 - year - old virologist who studied the West Nile virus
at the
Environmental Health Institute in Singapore came down with the
disease; an investigation blamed the infection on sloppy lab procedures
at the lab (ScienceNOW, 23 September).
Johnson's present position as a postdoctoral fellow
at Duke University allows her to conduct research on genetic and
environmental determinants in the development of Alzheimer's
disease and examine the differences across ethnicities.
«What that means to long term health and certain
diseases, we don't know yet,» says coauthor Heather Stapleton, an
environmental chemist
at Duke University.
The next step is to explore in detail the factors and mechanisms that link the two
diseases, and confirm that these findings are applicable to other geographic areas, where different
environmental and genetic factors are
at play.
«This study has provided more evidence to support the idea that
environmental factors, including influenza may be involved in Parkinson's
disease,» says Richard J. Smeyne, Ph.D., Professor of Neuroscience in the Sidney Kimmel Medical College at Thomas Jefferson University and Director of the Jefferson Parkinson's Disease Center in the Vickie and Jack Farber Institute for Neuros
disease,» says Richard J. Smeyne, Ph.D., Professor of Neuroscience in the Sidney Kimmel Medical College
at Thomas Jefferson University and Director of the Jefferson Parkinson's
Disease Center in the Vickie and Jack Farber Institute for Neuros
Disease Center in the Vickie and Jack Farber Institute for Neuroscience.
They also used World Health Organization spreadsheets «that would tell us how many people would develop cardiovascular
disease or mild mental retardation from those levels,» sayslead author Kevin Chatham - Stephens, a pediatrician
at The Mount Sinai Hospital who focuses on
environmental health.
«Crohn's
disease is a complex disorder with multiple genes and
environmental factors involved, which disproportionally affects individuals of Ashkenazi Jewish ancestry,» explained lead researcher Inga Peter, Professor of Genetics and Genomic Sciences
at the Icahn School of Medicine
at Mount Sinai in New York City.
«An individual's telomere length
at birth is known to influence their risk for
disease decades later during adulthood,» says Tang, professor of
Environmental Health Sciences
at the Mailman School.
Recent research suggests one benefit of
environmental enrichment
at the cellular level: it repairs brain myelin, the protective insulation surrounding axons, or nerve fibers, which can be lost because of aging, injury or
diseases such as multiple sclerosis.
«Getting health care providers to pay for home - based interventions is going to be necessary if we want to make a dent in the asthma problem,» said Patrick Breysse, a former Hopkins official, who as director of the National Center for
Environmental Health
at the Centers for
Disease Control and Prevention is one of the country's top public health officials.
«It's certainly plausible that any outside source that alters estrogen levels, even slightly, could contribute to gynecological
diseases,» said Dr. Megan Schwarzman, a family physician
at San Francisco General Hospital and an
environmental health scientist
at the University of California, Berkeley.
EPIC, as it's known, is a massive study aimed
at linking diet, lifestyle, and
environmental factors to the incidence of cancer and other chronic
diseases.
We need studies like this to find out how the two are intertwined and hopefully find the right formula to help prevent Alzheimer's
disease,» said Dr. Rong Zhang of UT Southwestern, who oversees the clinical trial and is Director of the Cerebrovascular Laboratory in the Institute for Exercise and
Environmental Medicine
at Texas Health Presbyterian Hospital Dallas, where the Dallas arm of the study is being carried out.
This can result in a serious genetic
disease that can cause anemia, neuro - cognitive impairment, and even early death,» says the study's lead - author, Dr. Jean - Louis Guéant, director of the Inserm unit of Nutrition - Genetics -
Environmental Risks
at University of Lorraine and head of the Department of Molecular Medicine and Personalized Therapeutics - National Center of Inborn Errors of Metabolism
at the University Regional Hospital of Nancy.
«Microbiology is coming to a point where it's extraordinarily evident that bacteria, fungi and viruses play a massive role in the development of health and
disease in humans, in
environmental settings and ecological systems,» said Jack Gilbert, PhD, associate professor in the Department of Ecology & Evolution
at the University of Chicago.
When Skinner and his colleagues exposed gestating rats to methoxychlor
at a range typical of high
environmental exposures, they saw increases in the incidence of kidney
disease, ovary
disease and obesity in offspring spanning three generations.
Such information could then be used to help tease out factors that put a person
at risk for developing a
disease, whether genetic or
environmental, or give insight into whether an intervention is working.