Sentences with phrase «enzyme aldose reductase»

[13] Mechanisms that may account for lipoic acid's benefit in preventing diabetic complications include prevention of protein glycosylation [14] and inhibition of the enzyme aldose reductase, the latter of which subsequently inhibits conversion of glucose and galactose to sorbitol.

Not exact matches

The research, Srivastava said, shows that using aldose reductase, an enzyme, when used with doxorubicin, reduces the toxins that can damage the heart.

«The discovery that aldose reductase regulates mucus production and goblet cell metaplasia makes inhibition of this enzyme an attractive therapeutic option to reduce mucus - related airway obstructive diseases — and for the first time gives us a real chance to alter the course of the underlying disease in asthma and COPD.»

Using cell culture and laboratory mouse experiments, the researchers showed that the enzyme, aldose reductase, is essential to a process known as goblet cell metaplasia that is seen in both asthma and COPD.

Researchers have proved that a single «master switch» enzyme, known as aldose reductase, is key in producing excess mucous that clogs the airways of people with asthma and chronic obstructive pulmonary disease (COPD).

Aldose reductase is the first enzyme in the sorbitol - aldose reductase (polyol) pathway [12] responsible for the reduction of glucose to sorbitol, as well as the reduction of galactose to galacAldose reductase is the first enzyme in the sorbitol - aldose reductase (polyol) pathway [12] responsible for the reduction of glucose to sorbitol, as well as the reduction of galactose to galacaldose reductase (polyol) pathway [12] responsible for the reduction of glucose to sorbitol, as well as the reduction of galactose to galactitol.

Any extra glucose that is absorbed into the lens is converted to sorbitol by an enzyme called aldose reductase.