Oleocanthal exhibits the same anti-inflammatory response in the body as the non-steroidal anti-inflammatory ibuprofen by inhibiting the
inflammatory enzymes cyclooxygenase - 1 (COX - 1) and cyclooxygenase - 2 (COX - 2).
At the same university, a follow - up study found that pine bark extract also inhibits COX - 1 and COX - 2 (forms of
the enzyme cyclooxygenase) 4.
As I illustrated above, arachidonic acid is processed by
the enzyme cyclooxygenase (COX) to produce pro-inflammatory signaling molecules called eicosanoids, including leukotrienes, prostaglandins, and thromboxanes.
They work by blocking
the enzyme cyclooxygenase, which generates prostaglandins, according to MedicineNet.
Anti-Inflammatory Effects: Eugenol (one of basil's volatile oils) can also help block
the enzyme cyclooxygenase (COX) in the body.
'' [NSAIDs] are strong inhibitors of
the enzyme cyclooxygenase — COX — which is an important enzyme that is responsible for producing inflammatory mediators,» Etminan says.
Nonsteroidal anti-inflammatory drugs mainly target
the enzyme cyclooxygenase.
If
the enzyme cyclooxygenase 1 (COX 1) transforms arachadonic acid, PG E1 prostaglandin is produced.
The study showed that the combination of NMX1000 ® avocado / soybean unsaponifiables, FCHG49 ® glucosamine hydrochloride, and TRH122 ® low molecular weight chondroitin sulfate decreased expression of
the enzyme cyclooxygenase - 2 that regulates the production of the mediator prostaglandin E2 (PGE2) in both equine chondrocytes and equine osteoblasts.
NSAIDs like Deramaxx repress
the enzyme cyclooxygenase (COX).