Sentences with phrase «enzyme cytidine deaminase»

Bacteria that produce the enzyme cytidine deaminase converted the drug to an inactive form.

Not exact matches

As these cells rapidly proliferate, they also express high levels of an enzyme known as activation - induced cytidine deaminase (AID), which induces mutations in their DNA.

Liu and coworkers developed last year's base editor by combining three proteins: a cytidine deaminase, a natural enzyme that converts C to uridine (U); a mutated Cas9 CRISPR enzyme that doesn't cut DNA but uses an associated guide RNA to target specific DNA sequences; and a protein that prevents reversion of U back to C.