Not exact matches
The symposium will cover this fascinating and often neglected field from lipid biology and
phosphoinositide signaling to membrane transport and intramembrane
enzymes.
Using standard
enzyme - linked immunosorbent assays (ELISA) and peripheral blood mononuclear cell (PBMC) assays, researchers discovered that unlike previously described human antibodies to lipids, WR321 did not react with any of 17 other lipids it was tested against, including cholesterol, glycolipids, and other phospholipids such as cardiolipin and phosphatidylserine, but it bound specifically only to two
phosphoinositides.
PLC - beta is a 150 kDa
enzyme that catalyzes the hydrolysis of
phosphoinositide PtdIns (4,5) P2 located in the plasma membrane into diacylglcyerol (DAG) and Ins (1,4,5) P3.