Sentences with phrase «ephrin pathway»
Disrupting either the Wnt or ephrin pathway throws the growing axons off their targets, shifting the map from side to side.
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«This might mean that strategies to control exosome release could be used to interrupt the ephrin - Eph signaling pathway and thereby disrupt tumour growth,» he surmises.
Ephrin - B reverse signaling is required for formation of strictly contralateral auditory brainstem pathways.
Syk kinases are required for spinal commissural axon repulsion at the midline via the ephrin / Eph pathway.
More recently, we elucidated an additional mechanism of tumor suppression mediated by canonical ephrin - induced EphA2 signaling (Figure 1A), which leads to inhibition of the AKT - mTORC1 oncogenic pathway through interplay of EphA2 with a phosphatase that dephosphorylates the AKT serine / threonine kinase.