Sentences with phrase «epiblast stem»

Now, they're working to see if the MM - 401 eraser technique works with human stem cells that bear some resemblance to mouse epiblast stem cells.

The epiblast stem cells on top have begun to differentiate, but when treated with the drug, they revert to an»em bryonic» - like state, as seen at bottom.

Writing in the journal Cell Stem Cell, the team reports that more than half of mouse epiblast stem cells treated with the drug reversed course within three days, and regained an embryonic «be anything» state, also called pluripotency.

As a postdoctoral fellow at the National Institute of Neurological Disorders and Stroke at the National Institutes of Health he discovered epiblast stem cells.

Not exact matches

Hayashi then drew on other research showing that one key regulatory molecule (activin A) and a growth factor (basic fibroblast growth factor) could convert cultured early embryonic stem cells into cells akin to epiblasts.

Niakan and colleagues predicted from earlier work with mice and human embryonic stem cells that the protein OCT4 would be necessary for the epiblast cells to develop correctly.

Mouse embryonic stem cells derived from the epiblast contribute to the somatic lineages and the germline but are excluded from the extra-embryonic tissues that are derived from the trophectoderm and the primitive endoderm upon reintroduction to the blastocyst.