Sentences with phrase «epidermal equivalents»

Human epidermal equivalents representing different types of skin could also be grown, depending on the source of the stem cells used, and could thus be tailored to study a range of skin conditions and sensitivities in different populations.»

These keratinocytes were then used to manufacture 3D epidermal equivalents in a high - to - low humidity environment to build a functional permeability barrier, which is essential in protecting the body from losing moisture, and preventing the entry of chemicals, toxins and microbes.

Dr Dusko Ilic, leader of the team at King's College London, says: «Our new method can be used to grow much greater quantities of lab - grown human epidermal equivalents, and thus could be scaled up for commercial testing of drugs and cosmetics.

A comparison of epidermal equivalents generated from iPSC, hESC and primary human keratinocytes (skin cells) from skin biopsies showed no significant difference in their structural or functional properties compared with the outermost layer of normal human skin.