Speaker: Dr. Dorothy Supp Title: The role of
epidermal keratinocytes in keloid scarring.
Canine progenitor
epidermal keratinocytes express various inflammatory markers, including interleukin - 8 and CD40, which are affected by certain antibiotics.
The research, described in the journal Stem Cells under the title «Reprogramming Postnatal Human
Epidermal Keratinocytes Toward Functional Neural Crest Fates,» was supported by grants from the National Institutes of Health.
Rubella persistence in
epidermal keratinocytes and granuloma M2 macrophages in patients with primary immunodeficiencies.
Not exact matches
A comparison of
epidermal equivalents generated from iPSC, hESC and primary human
keratinocytes (skin cells) from skin biopsies showed no significant difference in their structural or functional properties compared with the outermost layer of normal human skin.
These
keratinocytes were then used to manufacture 3D
epidermal equivalents in a high - to - low humidity environment to build a functional permeability barrier, which is essential in protecting the body from losing moisture, and preventing the entry of chemicals, toxins and microbes.
Wei Long Ng explained: «The two - step bioprinting strategy involves the fabrication of hierarchical porous collagen - based structures (that closely resembles the skin's dermal region), and deposition of
epidermal cells such as
keratinocytes and melanocytes at pre-defined positions on top of the biomimetic dermal skin constructs, to create 3D in - vitro pigmented human skin constructs.
Ng explains, «The two - step bioprinting strategy involves the fabrication of hierarchical porous collagen - based structures (that closely resembles the skin's dermal region), and deposition of
epidermal cells such as
keratinocytes and melanocytes at pre-defined positions on top of the biomimetic dermal skin constructs, to create 3D in - vitro pigmented human skin constructs.
Firstly, 27 nutritional components were screened in vitro for their ability to up - regulate
epidermal lipid synthesis, using cultured canine
keratinocytes (Watson et al. 2006).