Sentences with phrase «epigenetic age»
Results indicated that intervention effects on reductions in harsh parenting accounted for the association between parental depression levels and slower epigenetic aging among offspring.
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Interestingly, their children also have younger - than - expected epigenetic ages, which suggests they're aging more slowly, too.
Obesity accelerates epigenetic aging of human liver.
«Genome wide association study of epigenetic aging rates in blood reveals a critical role for TERT.»
Then we studied the SNPs that had very significant associations with epigenetic aging rates.
The purpose of this study was to determine whether the Strong African American Families (SAAF) heightened parental depressive symptoms would forecast accelerated epigenetic aging for youths.
«We can't conclude definitively from our study that the insomnia leads to the increased epigenetic age, but these are powerful findings,» said Carroll.
Decreased epigenetic age of PBMCs from Italian semi-supercentenarians and their offspring.
Every iPSC line had a negative predicted epigenetic age, as expected, but the team also noticed age - related variation.
Limitations include SAAF trial was not designed with epigenetic aging as an endpoint, may not be generalizable to rural African American families in other geographic regions or from dissimilar socioeconomic backgrounds, and lack of follow - up.
about Genome Wide Association Study of Epigenetic Aging Rates in Blood Reveals a Critical Role for TERT
People with HIV infection or Down syndrome — conditions that put them at risk for early heart disease and dementia — have older - than - expected epigenetic ages.
In this genome - wide association study, researchers found gene variants mapping to five loci associated with intrinsic epigenetic age acceleration (IEAA) and gene variants in three loci associated with extrinsic epigenetic age acceleration.
Next, we related the epigenetic aging rate to millions of genetic locations (SNPs) across all of the chromosomes.
Co-author Douglas P. Kiel, M.D., M.P.H, Director, Musculoskeletal Research Center and Senior Scientist at Hebrew SeniorLife's Institute for Aging Research said, «We calculated the epigenetic aging rate for each person using a previously described epigenetic clock method.
The research team analyzed the epigenetic age of up to 30 anatomic sites from the 112 - year - old woman.
He calculated the epigenetic age of specific organs and discovered that body parts can age at different rates.
«In children, we think slower epigenetic aging might indicate an inability to thrive,» said Michael Kobor, a Professor in the UBC Department of Medical Genetics who leads the «Healthy Starts» theme at BC Children's Hospital Research Institute.
The children who experienced higher distress and received relatively little contact had an «epigenetic age» that was lower than would be expected, given their actual age.
On the other hand, people who live to be 100 have epigenetic ages that are nine years younger, on average, than their actual age.
Family - centered prevention ameliorates the longitudinal association between risky family processes and epigenetic aging.
Supportive Family Environments Ameliorate the Link Between Racial Discrimination and Epigenetic Aging.