Sentences with phrase «epigenetic clock»

Co-author Douglas P. Kiel, M.D., M.P.H, Director, Musculoskeletal Research Center and Senior Scientist at Hebrew SeniorLife's Institute for Aging Research said, «We calculated the epigenetic aging rate for each person using a previously described epigenetic clock method.

Epigenetic clocks indicate that the offspring are about five years younger biologically than other people of the same chronological age.

The most accurate epigenetic clock looks at 353 methylation sites out of millions on our chromosomes.

Conclusions: Here we identify and characterise an epigenetic predictor of age in mice, the mouse epigenetic clock.

Variants in the gene called Telomerase Reverse Transcriptase (TERT) on chromosome 5 that were associated with older IEAA were also associated with longer telomeres indicating a critical role for TERT in regulating the epigenetic clock, in addition to its established role of compensating for cell replication - dependent telomere shortening.

«For those people who age more slowly, somehow their epigenetic clock ticks more slowly,» Horvath says.

«There's an intrinsic process that drives aging, and that may be what's captured by this epigenetic clock.»

Subsequent research on Italian centenarians revealed that the offspring of these centenarians were substantially younger, up to about five years, according to their epigenetic clocks, than the progeny of non-centenarians.

The Epigenetic Clock «There's a knot in here that's going to give you trouble,» Jose Valencia warns me, speaking in Spanish through an interpreter while he massages the fleshy pad of skin between my left thumb and index finger, then flashes a mischievous, toothy grin, as if to tell me I'd better be careful.

Since then, he has used the epigenetic clock as a tool to begin to understand the mechanics of aging.

HIV - 1 infection accelerates age according to the epigenetic clock.

The cerebellum ages slowly according to the epigenetic clock.

Instead we can use the epigenetic clock to monitor their cells» aging rate and to evaluate which therapies slow the biological aging process,» explained Horvath.

While both studies are bad news for many women, Horvath suggests that scientists in the future may use the epigenetic clock as a diagnostic tool to evaluate the effects of therapies, like hormone therapy for menopause.

Using the epigenetic clock, they found that postmenopausal women with five insomnia symptoms were nearly two years older biologically than women the same chronological age with no insomnia symptoms.

A newer and more informative measure is known as the epigenetic clock.

Scientists can read these DNA - methylation patterns (aka «epigenetic clock» or «DNA methylation age») to accurately estimate your age without any additional information about you.