So, thanks to a Catalan government ICREA (Catalan Institution of Research and Advanced Studies) award, designed to lure senior scientists working abroad to the region, this up - and - coming Italian researcher will shortly move to CRG to lead a group studying
epigenetic events in cancer.
«It is expected that this study will lay the foundation for developing a new class of potent and effective cancer therapies and the development of reagents targeting
epigenetic events in immune - mediated diseases as well as other epigenetically - influenced diseases,» said Alani, who also is chief of dermatology at Boston Medical Center.
Not exact matches
, 1968 Zick Rubin, «The Social Psychology of Romantic Love», 1969 Elliot Aronson, «Some Antecedents of Interpersonal Attraction», 1970 David C. Glass and Jerome E. Singer, «The Urban Condition: Its Stresses and Adaptations — Experimental Studies of Behavioral Consequences of Exposure to Aversive
Events», 1971 Norman H. Anderson, «Information Integration Theory: A Brief Survey», 1972 Lenora Greenbaum, «Socio - Cultural Influences on Decision Making: An Illustrative Investigation of Possession - Trance
in Sub-Saharan Africa», 1973 William E. McAuliffe and Robert A. Gordon, «A Test of Lindesmith's Theory of Addiction: The Frequency of Euphoria Among Long - Term Addicts», 1974 R. B. Zajonc and Gregory B. Markus, «Intellectual Environment and Intelligence», 1975 Johnathan Kelley and Herbert S. Klein, «Revolution and the Rebirth of Inequality: The Bolivian National Revolution», 1977 Murray Melbin, «Night as Frontier», 1978 Ronald S. Wilson, «Synchronies
in Mental Development: An
Epigenetic Perspective», 1979 Bibb Latane, Stephen G. Harkins, and Kipling D. Williams, «Many Hands Make Light the Work: The Causes and Consequences of Social Loafing», 1980 Gary Wayne Strong, «Information, Pattern, and Behavior: The Cognitive Biases of Four Japanese Groups», 1981 Richard A. Shweder and Edmund J. Bourne, «Does the Concept of the Person Vary Cross Culturally?»
«There's a complex interplay between hormones, experience and
epigenetic changes
in response to life
events,» says neuroscientist Cheryl Sisk, who studies sex differences
in the brain at Michigan State University
in East Lansing.
It might be possible then to link the alterations to environmental changes such as stressful
events or diet, which have been shown to cause inheritable
epigenetic changes
in mice.
The new finding is the latest evidence supporting a growing precision medicine model of psychiatric disease
in which disruptions of certain genes during brain development contribute to a person's risk for multiple psychiatric disorders, with other genetic or
epigenetic drivers, random developmental
events, or environmental influences determining the specific disease an individual develops, said senior author Benjamin Cheyette, MD, PhD, an associate professor of psychiatry and a member of the UCSF Weill Institute for Neurosciences and the Kavli Institute for Fundamental Neuroscience at UCSF.
Professor Wolf Reik, Head of the
Epigenetics research programme, said: «Charting the different developmental timings
in the early reprogramming
events observed
in the human and mouse - derived cells gives the first mechanistic insight into how these
events are regulated which is tremendously exciting.
The next steps are to capture what happens
in the later stages of primordial germ cell development and the related
epigenetic events.
«Most of the scientific community
in Spain is looking with sadness to the current
events,» Manel Esteller, director of the Cancer
Epigenetics and Biology Program at the Bellvitge Biomedical Research Institute
in Barcelona, writes
in an e-mail to ScienceInsider.
Chromatin structure and function as well as
epigenetic processes play key roles
in regulating pluripotency and early differentiation
events.
It is therefore reasonable to suggest that genetic and
epigenetic risk analysis could soon become part of the recruitment equation to protect vulnerable individuals from future exposure or provide those individuals with adequate immediate help
in the case of a traumatic
event.
The Lieber Institute for Brain Development, the Johns Hopkins Bloomberg School of Public Health, and the University of Maryland School of Medicine and Center for
Epigenetic Research
in Child Health and Brain Development are hosting the one - day symposium
event.
In fact, as you'll learn in an upcoming article, epigenetic changes may also be triggered by events that happened to your parents, grandparents or even great - grandparents, who passed the faulty on / off switch along to you through your DN
In fact, as you'll learn
in an upcoming article, epigenetic changes may also be triggered by events that happened to your parents, grandparents or even great - grandparents, who passed the faulty on / off switch along to you through your DN
in an upcoming article,
epigenetic changes may also be triggered by
events that happened to your parents, grandparents or even great - grandparents, who passed the faulty on / off switch along to you through your DNA.
Although the mechanism of age - related decline
in DNA repair capacity is unknown, growing evidence suggests that
epigenetic events (e.g., DNA methylation) contribute to the ageing process and may be functionally important through the regulation of the expression of DNA repair genes.
The research provides further evidence that genetic and
epigenetic events are both important
in establishing different subgroups of ALL.
Pro-survival
events presumably arise through genetic and
epigenetic changes induced by non-viral mechanisms
in EBV - negative BLs.
Dynamic
epigenetic regulations of the Gdnf gene play significant roles
in identifying both the susceptibility and the adaptation responses to chronic stressful
events.
Epigenetic status of Gdnf
in the ventral striatum determines susceptibility and adaptation to daily stressful
events