Sentences with phrase «epigenetic information»
The researchers then showed that new environmental conditions, such as a different ambient temperature, can affect the expression of epigenetic information over several generations, but they do not erase this information.
sciencedaily.com
Beyond the DNA sequence, so - called epigenetic information contributes to the control of gene expression.
The genetic information of the DNA is passed on along with the relevant epigenetic information for the respective cell type.
This is the first time an epigenetic signal has been shown to impact ubiquitylation and connects the patterns of epigenetic information in a new way.
In the current paper, Ren and his colleagues describe their use of μChIP - seq to investigate how epigenetic information is passed from one generation to the next to orchestrate the MZT.
Researchers have uncovered previously unappreciated means by which epigenetic information contained in the egg influences the development of the placenta during pregnancy.
BETHESDA, MD — An algorithm using epigenetic information from just nine regions of the human genome can predict the sexual orientation of males with up to 70 percent accuracy, according to research presented at the American Society of Human Genetics (ASHG) 2015 Annual Meeting in Baltimore.
With these results the study by the Max Planck researchers is an important step forward and shows clearly the biological consequences of inherited epigenetic information.
It is now well - established that DNA sequence is complemented by epigenetic information including DNA methylation and histone modifications to program gene expression [24].
Specifically, the study reveals a mechanism that helps explain how dividing cells pass patterns of epigenetic information called methyl tags to their daughter cells, a crucial part of regulating gene expression across cell generations.
«We saw indications of intergenerational inheritance of epigenetic information since the rise of the epigenetics in the early nineties.
«We think maybe specific epigenetic information is transmitted to the germ line stem cell and to the gonialblast.»
TMWG allows customers to access the power of whole - genome epigenetic information in an integrated, cost - effective solution combining state - of - the art sample preparation and DNA sequence analysis.
Over a decade after its initial funding, The Cancer Genome Atlas has concluded this month with the most comprehensive analysis of TCGA data, cataloguing DNA alterations, gene expression and epigenetic information across thousands of tumours as part of the PanCanAtlas effort.
It seems, virtually, that inherited epigenetic information is needed to process and correctly transcribe the genetic code of the embryo,» explains Fides Zenk.
Critical Issues in the Inclusion of Genetic and Epigenetic Information in Prevention and Intervention Trials.
The chemical modification of histones is thought to be a form of epigenetic information — information separate from our DNA — that controls gene regulation.
The findings center on a protein called UHRF1, a guardian of the cell's epigenetic information that can recognize patterns of epigenetic tags and promote the addition of new ones.
«Just as normal cells with the same genome differentiate into many different cell types, a single tumor characterized by specific genetic mutations can contain many different types of cells — stem - like and more differentiated cells — with the difference being rooted in their epigenetic information.
«There must be another hidden carrier of epigenetic information that we don't know about.»
«It turned out that, in reproduction, epigenetic information is not only inherited from one generation to another but also important for the development of the embryo itself,» says Nicola Iovino.
Epigenetic information is not encoded within the DNA sequence but is critical for determining which genes are on or off.
Researchers suggest future generations could benefit from this «epigenetic information» as climate change causes global temperatures to rise.
It has been appreciated in the last decade that, just like errors in the genetic language itself, failure to maintain the epigenetic information can cause human disease, such as developmental disorders or cancer».
The researchers say they've found evidence that obesity changes the microRNA (miRNA) signature — epigenetic regulators of gene expression — in both the dad's sperm and the daughter's breast tissue, suggesting that miRNAs may carry the epigenetic information from obese dads to their daughters.
The Mattiroli group studies chromatin dynamics during DNA replication to understand how the epigenetic information is faithfully propagated during cell division.
Aberrant regulation of the epigenetic information results in changes in cell fate decisions, thereby affecting development and tissue homeostasis, and ultimately leading to disease, such as cancer.
The questions, which are currently being researched, are how much and which part of the epigenetic information is preserved and subsequently inherited.
While we understand how the genetic information is replicated in S phase, we lack mechanistic knowledge on how the epigenetic information, specifically histone post-translational modifications in nucleosomes, are propagated to daughter cells.
Her group investigates the mechanisms that control inheritance of the epigenetic information contained in nucleosomes, during cell division and in situation of DNA damage.
During cell division, accurate propagation of the epigenetic information is thus essential for cell survival and disease avoidance.
In eukaryotes, chromatin organizes the genetic and epigenetic information of the cell.
The epigenetic information ensures the spatial and timely organization of gene transcription that determines cell identity.
Researchers suggest future generations could benefit from this «epigenetic information» as climate change causes global temperatures to rise.