This so -
called epigenetic level of control is based on the localized, and in principle reversible, attachment of simple chemical tags to specific nucleotides in the genome.
DNA methylation is a mechanism cells use to control gene expression at
the epigenetic level.
Now, new research suggests changes at
the epigenetic level — specifically alterations in proteins that affect gene expression, rather than genetic mutations — could be driving childhood ependymomas.
Hackermüller suspects that non-coding RNAs have an important function at
the epigenetic level, for example as a type of cellular long - term memory: «This could also explain why the health effects caused by exposure to hazardous environmental substances often do not emerge until years later.»
Conversely, the machinery responsible for modifying DNA and histones at
the epigenetic level is highly sensitive to metabolites arising from cellular metabolism.
As reported in the latest issue of Developmental Cell, the researchers developed a method to generate primordial germ cell «lookalike» cells to look in detail at what was happening at
the epigenetic level, comparing what happens in cells from mice and humans.
Now, the Journal of Neuroscience Research is dedicating an issue entirely to sex differences at all levels of the brain, from the genetic and
epigenetic level, to the synaptic, cellular, and systems levels.
Bonni and his colleagues showed that NuRD exerts influence at
the epigenetic level, which means it controls factors other than DNA that affect gene activity.
Here, we present evidence that HIV - 1 latency is also maintained at
the epigenetic level by the methylation of provirus DNA and recruitment of MBD2.
-- In silico basic and systems biology: We develop innovative approaches to reverse engineer biological networks from omics data, model tumor progression at the genomic, transcriptomic and
epigenetic level, automatically annotate new proteins and functional elements through integration of complex and heterogeneous data, including data obtained from high - throughput sequencing or time - lapse video - microscopy.
Hurley said adaptation to salt is likely affecting Daphnia at
the epigenetic level, a heritable change in gene levels rather than genetic code.
How does regulation of gene expression determine inner ear function on a genetic and
epigenetic level?
And the soy peptide lunasin is the first dietary ingredient identified to affect gene expression and promote optimal health at
the epigenetic level.
Despite years of reading on the general topic of antioxidant protection, this video put everything together at the most fundamental,
epigenetic level.
Live Science reports on Yahoo News that «rather than changing their genes, a new study finds, Tasmanian devil tumors are altering on
an epigenetic level — meaning the basic gene sequences stay the same, but the genes that get switched on and off are different.
So in a real sense, the function of a real estate agent hits to
an epigenetic level via some of our most basic and fundamental needs and motivations.