Sentences with phrase «epigenetic machinery»
The phrase "epigenetic machinery" refers to the biological processes and molecular components within our cells that can affect how our genes are switched on or off, without changing the DNA sequence itself. It is like a system or set of tools that can modify how our genes are expressed, leading to different traits or characteristics. Full definition
«Some breast cancer tumors hijack patient epigenetic machinery to evade drug therapy.»
sciencedaily.com
Both of these methods also recruit epigenetic machinery - but is there an advantage to using direct epigenetic modifiers?
Some viral pathogens modify chromatin and other epigenetic machinery, making them appealing drug targets.
Dr Tomi Pastinen, senior author on the second study, from McGill University said: «We have created an expansive, high - resolution atlas of variations that deepens our understanding of the interplay between the genetic and epigenetic machinery that drives the three primary cells of the human immune system.
Thus, the metabolic changes associated with oncogenesis may affect the epigenetic machinery, creating a feedback loop that synergistically promotes the progression of cancer.
These non-coding fragments of RNA may help to guide the epigenetic machinery to specific locations on DNA.
Diagnose and provide optimal care for patients with either classical epigenetic disorders or mutations of the epigenetic machinery.
Her current research focuses on abnormal growth caused by aberrations in the epigenetic machinery.
She examines how a mutation in the EZH2, a component of the epigenetic machinery, leads to Weaver syndrome, a genetic disorder characterized by excessive skeletal and organ growth, as well as intellectual disability.
Educate health providers and patients about epigenetics and the disorders of the epigenetic machinery.
These Mendelian disorders of the epigenetic machinery are genetic disorders expected to have widespread epigenetic consequences.
In the last several years a number of genetic defects involving various components of the epigenetic machinery have been uncovered.