Sentences with phrase «epigenetic modifications contribute»
Scientists have long suspected that epigenetic modifications contribute to cancer.
https://www.sciencenews.org/ Not exact matches
These epigenetic modifications do not change the genetic code, but may contribute to the inhibition of gene expression, causing the cells to produce smaller amounts of the corresponding proteins.
«Recent studies suggest that epigenetic modifications may contribute to the development of cancer progenitor cells that can induce drug resistance and the relapse of different types of cancer,» said Sibaji Sarkar, PhD, instructor of medicine at BUSM.
Schrock: I'm sure that's been tried, but one of the new things they found is this specific tie between the circadian rhythm in our bodies and drug addiction and they found that it is actually through an epigenetic modification of the circadian rhythm; so our circadian rhythms are reset by these drugs; we actually crave them at certain times of day and that is contributing to the necessity to, you know, relapse and go back on drugs or to get that craving, you know, at a certain point.
Disruption of a region in chromosome 6 or epigenetic modifications of the DNA block Sestrin1 expression and these contribute to the development of Follicular Lymphoma.
Our work thus contributes to the understanding of aberrant histone modification in peripheral T - cell lymphomas, not otherwise specified and the stratification of a biological subset that can benefit from epigenetic treatment.
Throughout the 2000s, Wistar scientists made seminal discoveries in the field of epigenetics and RNA transcription, contributing new knowledge on the role of histone modifications in gene regulation and DNA repair and how different RNA species, including microRNAs (miRNA) and long noncoding RNAs (lncRNA), are generated and how they regulate gene transcription.
«Recent studies suggest that epigenetic modifications may contribute to the development of cancer progenitor cells that can induce drug resistance and the relapse of different types of cancer,» said Sibaji Sarkar, PhD, instructor of medicine at BUSM and the article's corresponding author.