Sentences with phrase «epigenetic processes»

The second aspect deals with the importance of epigenetic processes in the female germ line.

Furthermore, animal studies suggest that harsh parenting affects the expression of genes by epigenetic processes.

However, scientists have recently found that gene regulation can also happen in an ongoing fashion through epigenetic processes, with the potential to change behavior throughout a lifetime.

His current research focuses on infant memory for stress and epigenetic processes affecting behavior.

Several laboratories that explore such epigenetic processes have productively focused on genes in the glucocorticoid system (19 ⇓ — 21).

To understand why some individuals exhibit characteristics of a resilient profile, the interplay between neurochemical, genetic, and epigenetic processes over time needs to be explained.

Methylation is among the so - called epigenetic processes — those not specifically designed to affect the genes — that can alter chromatin.

The black truffle uses reversible epigenetic processes to regulate its genes, and adapt to changes in its surroundings.

In both cases, he relied on epigenetic processes — using groups of chemicals called acetyl groups to modify key proteins — but in opposite directions.

The researchers focused on one common epigenetic process known as methylation, in which methyl (CH3) groups attach in various patterns to the genes of human cells.

Ecker studies epigenetic processes in plants and animals, and is a leader in studies of methylation, in which small chemical tags called methyl groups are attached to specific sites in the genome.

Since HIV infection itself alters epigenetic processes in the immune system, the research team wondered whether a distinct DNA methylation profile, a major epigenetic modification where methyl groups are added to DNA, occurs in those with HIV associated - cognitive impairment and whether it exists in distinct immune cell populations from the blood.

Scientists call this particular epigenetic process methylation.

RNAi and other epigenetic processes induce changes in where and when specific genes are expressed without altering their genetic code...

Our genome - wide studies have found evidence for abnormal epigenetic processes, rather than direct gene mutations, that lead to such abnormal ncRNA / miRNA regulation.

These two observations suggest that worker reproduction is influenced by more plastic epigenetic processes than those of queen — worker differentiation — processes, it has been suggested, that could be analogous to somatic cell reprogramming and transdifferentiation [36].

Methylation, a fundamental epigenetic process whereby carbon groups are attached to DNA to either silence it or promote its expression, is quintessential to cellular processes including detoxification, metabolism, neurotransmitter synthesis, mitochondrial energy production, central nervous system function, cell cycle regulation, cellular integrity, and immune homeostasis — and derangements in methylation have been implicated in many diseases (Robertson, 2005).

«At this time, when prescription opioid use and opioid overdoses are both major threats to our public health, it is important to identify new treatment targets, such as epigenetic processes, that help to change the way that we do business in treating opioid use disorders,» said professor John Krystal, Editor of Biological Psychiatry.

Recent advances have shown that the ENVIRONMENT influences the genes through epigenetic processes, and fires and wires brain circuits, and also determines highly conserved behaviors necessary for fitness.

«Cancer - killing cells controlled by epigenetic process.»

Genetic factors drive this early overproduction of neurons, Schore explains, but the brain awaits direction from the social environment, or epigenetic processes, to determine which synapses or connections are to be pruned, which should be maintained, and which genes are turned on or off.

A new study in Biological Psychiatry found that heroin use is associated with excessive histone acetylation, an epigenetic process that regulates gene expression.

The scientists caution that their model, as is the case with any laboratory model, may not be exactly what occurs in people during a lengthy period of smoking, but they say it's a first step in understanding the epigenetic processes that may occur early in the transformation of cells into lung cancer.

Epigenetic processes are essentially switches that control a gene's potentially heritable levels of protein production but without involving changes to underlying structure of a gene's DNA.

«We need to readjust and think more broadly about the epigenetic process as a whole.»

«Although a central role for DNA methylation in development and disease has been well - documented, our results suggest that epigenetic processes can play an equally important role in adaptive evolution,» the team writes.

In the current study, researchers have shown that an epigenetic process, involving the attachment of a small protein to the histone H2B (called H2Bub1), facilitates an important structural change of the centromere immediately prior to cell division.

This means that what happens in utero may affect a person's brain development by the time they reach their teen years, and that epigenetic processes may play a role in this relationship.»

In actual fact, one of the lessons over the last 10 years is just how complicated these epigenetic processes are.

Fernald's work suggests that epigenetic processes may cause, rather than simply reflect, changes in dominance status in hierarchically organized species, said Tom Boyce, a professor at the University of California, San Francisco School of Medicine, who was not involved in the study.

Analyzing the data revealed surprises about the epigenetic processes of retinal neuron development, Dyer said.

Our study describes how an epigenetic process involving the enzyme MYSM1 plays a critical role in the development of natural killer cells.»

DNA methylation is an epigenetic process in which small molecules — methyl groups - are added to genes and fine - tune the gene's activity, like a dimmer switch.

In theory, this epigenetic process is reversible if the newly synthesized DNA strands are not methylated.

While epigenetic scientists have devoted most of their research to methylation, they've identified many different types of epigenetic processes.

A host of factors, in turn, causes the epigenetic processes that flip different genes on and off.

Epigenetics Dream Team leaders have identified an epigenetic process, known as DNA de-methylation, that inactivates or «silences» key genes that might otherwise correct for the «mistakes» that permit cancer to exist and flourish.

Specifically, the genome - wide systems biology approaches to dissect the epigenetic processes that become abnormal when aggressive prostate cancer and melanoma initiates, rather than the reductionist «gene - by - gene» classical approaches, are urgently necessary.

Chapters on genetic and epigenetic processes, executive functions, historical trauma, and neglect.

The Contributions of Maternal Sensitivity and Maternal Depressive Symptoms to Epigenetic Processes and Neuroendocrine Functioning.