Sentences with phrase «epigenetic profiles from»

De Jager said that researchers are devising ways to eke out epigenetic profiles from single cells, which would ultimately simplify the comparison of different neuronal types.

Not exact matches

The team found that exhausted T cells acquired an epigenetic profile distinct from effector or memory T cells.

By comparing the epigenetic profiles of gastric tumours to normal tissues from the same patient, we were able to identify those promoters specifically altered in GC tissues.»

Since HIV infection itself alters epigenetic processes in the immune system, the research team wondered whether a distinct DNA methylation profile, a major epigenetic modification where methyl groups are added to DNA, occurs in those with HIV associated - cognitive impairment and whether it exists in distinct immune cell populations from the blood.

A number of recent articles, however, have reported that hiPSCs are, in fact, notably distinct from human embryonic stem cells in terms of their gene expression, epigenetic profile, proliferative capacity and the susceptibility of their differentiated progeny to cellular senescence and apoptosis [3 — 6].

Concurrently, the research group is examining how the epigenetic profile of different candidate genes predicts, and perhaps changes, in response to recovery from PTSD (and negative self - cognitions) along with its neural correlates.

For example, prenatal maternal anxiety is associated with an altered function of the placenta, in a way that may allow more cortisol to pass from mother to fetus.8 This probably underlies some of the alterations in fetal and child brain neurodevelopment following early exposure to stress and may also be one of the mediators of an altered epigenetic profile, although many other biological systems, including serotonin, dopamine and the pro-inflammatory cytokines, are also likely to be involved.