Not exact matches
The data from the study demonstrate that KZFP partner up with transposable elements to create what the authors
call «a largely species - restricted layer of
epigenetic regulation.»
«For example, we now know that RNA can be methylated just like DNA and in a highly specific way,» says Dr. Manel Esteller, «and even more recently we observed that these
epigenetic modifications of RNA may be key in the
regulation of «guardian» RNAs, also
called non-coding RNAs.»
But to this base we must add some
regulation, just like the spelling and grammar of that alphabet: this is what we
call Epigenetics.
Hargreaves brings her knowledge of biochemistry and
epigenetic regulation to investigate a subunit of the SWI / SNF complex
called ARID1A, which is mutated in many solid tumors, such as in ovarian, bladder and colorectal cancers.
Petr Svoboda, 3rd
Call 2011 Institute of Molecular Genetics Department of
Epigenetic Regulations [email protected] +420 241063147
Through this packaging mechanism, researchers think that histone proteins are the key to regulating access to the genetic information by making different parts of the DNA accessible to factors that express the gene, so -
called epigenetic regulation.