Sentences with phrase «epigenetic regulation with»

01/29/2015: New paper on tissue - specific genetic & epigenetic regulation with Gutierrez - Arcelus et al. in PLoS Genetics

Not exact matches

Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse

«These new insights into the complexities of epigenetic regulation are contributing to our basic understanding of this process in human health and disease and gives us new vision for how to go about targeting errors in DNA methylation with innovative drug therapies.»

The data from the study demonstrate that KZFP partner up with transposable elements to create what the authors call «a largely species - restricted layer of epigenetic regulation.»

Rather the opposite was true, the altered epigenetic regulation of the gene was responsible for the development of the fatty liver,» added Sophie Saussenthaler, who shared the first authorship with Baumeier.

However, scientists have recently found that gene regulation can also happen in an ongoing fashion through epigenetic processes, with the potential to change behavior throughout a lifetime.

«Epigenetic changes in DNA regulation in early nutrition could provide a causal link with long - term health outcomes but need further investigation» said Lumey.

This altered expression that does not correlate with changes in the base sequence is known as epigenetic regulation (as opposed to genetic regulation).

Research Focus: I dedicate my time and effort to develop high - throughput sequencing technologies such as single cell transcriptomic, ChIP - Seq, ChIA - PET, and many more... The scientific rational is to understand better and with a different angle, the mechanisms of epigenetic regulation of gene expression in (rare) immune cells, pathologically relevant in many diseases such as asthma, SLE, tuberculosis...

These results are consistent with the emerging paradigm that epigenetic and transcription regulation frequently underlies the evolution of postzygotic hybrid dysfunctions [4], [5], [52], [53].

We also have research interests in cellular regulation by ADP - ribosylation, which links epigenetics to metabolism; lipid kinases; and sphingolipid biosynthesis, which has strong links to both inflammation and cancer, and where mutations in the various proteins involved are associated with a variety of rare diseases.

Xu is developing computational algorithms for the design and analysis of high - throughput biological experiments with a focus on applications in transcriptional and epigenetic gene regulation.

Epigenetic modifications in bacteria, such as DNA methylation, have been shown to affect gene regulation, thereby generating cells that are isogenic but with distinctly different phenotypes.

She collaborates with her colleagues at the University of Minnesota and University of Wisconsin - Madison on understanding genetic and epigenetic mechanisms in regulation of stress response in maize.

Previously, Dr. Ray completed her PhD at Harvard University with Dr. Robert Kingston, studying the effects of long non-coding RNAs on epigenetic regulation.

(a) Protective parenting will be associated with epigenetic regulation of inflammation via methylation of TNF resulting in a positive (+) association as well as with relative activation of innate vs. acquired immune responses via shifts in the relative proportion of different white blood cell types of different white blood cell types leading to a negative -LRB--) association.

McGowan, P.O., Sasaki, A., D'Alessio, A.C., Dymov, S., Labonte, B., Szyf, M., Turecki, G., Meaney, M.J. (2009) Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse.