Many other molecules are also
involved in this process, including
epigenetic regulators that help to densely pack the genome into the nucleus of a cell, or locally unpack it to allow gene expression.
Interestingly, the most commonly mutated set of genes were those
involved in
epigenetic modification (25 % of tumors) followed by transcriptional
regulators and MAP kinase - associated genes (12 - 15 %).