Sentences with phrase «epigenetic state»

And we are gaining more and more information as to how the drugs actually interact with that preexisting epigenetic state to lead to an addiction syndrome.
We have identified novel polymorphic variation that modifies epigenetic states, genome - wide expression levels, and reproductive phenotypes.
The integration of multi-scale knowledge and data is strongly encouraged including the analysis of gene expression, epigenetics, physiological function, pathological states, and drug and small molecule effects as a function of genetic and environmental and epigenetic state alterations.
These nutrients regulate the epigenetic state of the embryo.
The drug had no effect on the epigenetic state of DNA taken from the local metastasis but reversed the epigenetic changes seen in cells from the distant metastasis.
A mother's low protein diet while pregnant is therefore likely to have more severe consequence on the offspring's epigenetic state and weight than an offspring's own diet after it has been weaned.
Marlinde L. van den Boogaard conduct analyses suggesting transcription of DUX4 in somatic cells is modified by variations in its epigenetic state and provide a basis for understanding the reduced penetrance of Facioscapulohumeral dystrophy (FSHD) within families.
Various genomic structures and epigenetic states are known to shape and modify mutational landscapes across genomes [64].
Silvana Konermann et al. «Optical control of mammalian endogenous transcription and epigenetic states
For example, a recent study demonstrates differences in the epigenetic state (as evidenced by DNA methylation) of the Monoamine Oxidase A gene across Beagles, German Shepherds, and Sapsaree Dogs.
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