Sentences with phrase «epigenetic switches controlling»
The researchers used tools of epigenomic analysis to trace the specific epigenetic switches controlling each of thousands of genes in both mouse and human retinal cells as the cells progressed through development.
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Epigenetic processes are essentially switches that control a gene's potentially heritable levels of protein production but without involving changes to underlying structure of a gene's DNA.
The proposed strategy reflects a continuing move toward combination therapies, particularly when it comes to epigenetic approaches, which target the mechanisms that control whether genes are switched «on» or «off.»
The pair of studies bring renewed focus to the epigenetics of T cells — the multilayered system of molecular switches, accelerators, and throttles that controls the activity of genes.
One such surprise was the relative importance of two types of epigenetic control switches for retinal development.
Epigenetic controls are molecular switches that turn genes on or off to orchestrate a cell's development from a generic cell to a specialized cell like a neuron.