Sentences with phrase «epigenetic tags»

Older dads seem to pass on health risks via epigenetic tags on the DNA in their sperm.

Comparing one type of epigenetic tag known as DNA methylation in pairs of twins in which one brother is gay and the other straight revealed patterns that distinguish one group from the other about 67 percent of the time, computational geneticist Tuck Ngun and colleagues say.

Results of the unpublished study on the link between these modifications, called epigenetic tags, and sexual orientation were presented October 8 at the annual meeting of the American Society of Human Genetics.

On the outside of the heterochromatin bundles are chemical markers, known as epigenetic tags, which control the structure of the heterochromatin.

One possible intervention, he says, is administering micronutrients like folic acid that can alter epigenetic tags.

Epigenetic tags help tell genes — stretches of DNA that act as biological instruction manuals — when to switch «on» and «off,» ultimately determining cell type and function.

The researchers collected DNA from each sperm sample and looked for epigenetic tags at 450,000 different positions throughout the genome.

Dahl, a visiting scholar in Ren's lab and co-first author on the Nature paper, fine - tuned the technique for mapping such epigenetic tags to where only a few hundred embryos or cells were needed for each experiment.

The test, based on epigenetic tags on the genome, claims 67 per cent accuracy, but concerns over eugenics and misuse have led lead researcher to quit his job

The findings center on a protein called UHRF1, a guardian of the cell's epigenetic information that can recognize patterns of epigenetic tags and promote the addition of new ones.

However, in some studies with laboratory mice, Feinberg had observed that these epigenetic tags varied considerably among the mice even when comparing the same type of tissue in animals that have been living in the exact same conditions.

These new genes were created so they could not be the repositories of epigenetic tags or modifications.

And when the only functional Sfmbt2 gene carries these epigenetic tags, the intronic microRNA - 466b - 3p is silenced and can't keep watch over PEPCK as it normally would.

Imprinted genes use molecules that bind to DNA (epigenetic tags) to quiet one half and let the other lead.

Feinberg, Fallin and their team assessed the epigenetic tags on DNA from sperm from 44 dads.

In addition to being easier to sample than egg cells from women, sperm are more susceptible to environmental influences that could alter the epigenetic tags on their DNA.

Those studies showed that epigenetic tagging is different in cancer cells than in healthy cells.

In this study, investigators looked for possible causes for the condition not in genes themselves, but in the «epigenetic tags» that help regulate genes» activity.

The addiction - prone rats also were more likely to carry a specific mark on their DNA called an epigenetic tag.

And when the cocaine was taken away for a while, these rats were more likely to relapse to addictive behavior if they had started out with the epigenetic tag that kept their cells from reading the D2 gene.

Researchers working at the National Agriculture and Food Research Organization in Japan have found that epigenetic tags, such as methyl groups, on some areas of the plant genome can cause interference with gene editors and reduce their efficiency.

Gontier and colleagues found that as mice age, Tet2 levels in the hippocampus decline, as do the epigenetic tags Tet2 makes on DNA.

The other common form of epigenetic tag is called histone modification.