Sentences with phrase «epigenomic changes»

«However, there is emerging evidence that epigenomic changes such as DNA methylation and histone modifications, which affect the ways in which genes are transcribed and translated into proteins, are important features of these processes,» he continues.

«This is exactly the technology you could use to look for epigenomic changes in specific cell types,» says Martienssen, who is also on the International Human Epigenome Consortium's steering committee.

Not exact matches

Genetic data combined with information on gene expression and epigenomics in relevant tissues, and clinical information, can provide clues about the effects of genetic changes within an individual's genome that increase or decrease one's risk of developing type 2 diabetes and its complications, including heart and kidney disease.

Once finished, however, an epigenomic map could also prove useful in determining which individuals are at risk for certain diseases and encouraging the kind of lifestyle changes that can prevent the wrong genes from switching on or off.

From genomic and epigenomic sequences from a subset of the populations, we see changes in methylation patterns between the evolved populations over-represented in some functional categories of genes, which is consistent with some of these differences being adaptive.

These comprehensive epigenomic profiles enable us to understand the cause, function, and consequence of cancer - specific epigenetic changes.

This fascinating field of epigenomics examines how genes are modified without changing the DNA sequence — that is, how a gene for obesity, for instance, is modified by eating nonstarchy vegetables versus cupcakes.