Sentences with phrase «epigenomic features»
Moreover, the regional susceptibility and tolerance to a particular mutation type is a mixture of various genomic and epigenomic features and selective pressures [64].
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«However, there is emerging evidence that epigenomic changes such as DNA methylation and histone modifications, which affect the ways in which genes are transcribed and translated into proteins, are important features of these processes,» he continues.
Residing in large numbers outside the nucleus of every cell, mitochondria contain their own DNA, with unique features that «may require a reassessment of some of our core assumptions about human genetics and evolutionary theory,» concludes Wallace, director of the Center for Mitochondrial and Epigenomic Medicine at The Children's Hospital of Philadelphia.
The result is an epigenomic road map that links diseases and traits (red dots) with the locations in the body (white dots) of the switches most correlated with those features; thicker lines correspond to more robust links.
Called the Center for Epigenomics of the Mouse Brain Atlas (CEMBA), the project involves collecting information from more than 100 regions of the mouse brain, and linking them to features believed to be common to mammalian nervous systems in general.