The researchers enrolled
epilepsy patients at Wake Forest Baptist who were participating in a diagnostic brain - mapping procedure that used surgically implanted electrodes placed in various parts of the brain to pinpoint the origin of the patients» seizures.
Not exact matches
Scientists
at the University of Wisconsin and UCLA conducted the study, which implanted electrodes deep into the craniums of
epilepsy patients to monitor their brain activity during seizures.
The study — led by James Murrough, associate professor of psychiatry and director of the Mood and Anxiety Disorders Program
at Mount Sinai — chose the
epilepsy drug ezogabine, which was given to 18
patients in a pilot trial.
At much higher doses, benzodiazepines treat
epilepsy and anxiety in human
patients now, including those with autism.
«They may not look like a big deal from the outside, but if you listen in to the brain of a
patient having one of these seizures, you can hear that the brain is in seizure,» says Josef Parvizi, a Stanford neuroscientist and
epilepsy specialist who developed the brain stethoscope with colleague Chris Chafe, a music researcher
at Stanford.
Guideline authors noted, however, that the evidence for the recommendations is weak, since many of the studies had relatively small numbers of
patients with similar types of
epilepsy and were conducted
at only one institution, so the results may not be generalizable to everyone with
epilepsy.
Dravet
patients usually develop moderate to severe cognitive delays and some features of autism, and are
at increased risk of SUDEP (sudden unexplained death in
epilepsy).
In humans, this region could be a target for bringing some brain injury
patients out of a comatose state via electrical stimulation, says lead author Nigel Pedersen, MD, assistant professor of neurology
at Emory University School of Medicine and an
epilepsy specialist
at Emory Brain Health Center.
MBANs
at Home If all goes well, look for MBANs to fall into three categories in the near future — those used to monitor a
patient's general health or «wellness,» those measuring the health of the elderly, and those used to monitor
patients with long - term medical conditions such as Parkinson's disease or
epilepsy, says Paolo Bonato, director of the Motion Analysis Laboratory
at Boston's Spaulding Rehabilitation Hospital and an assistant professor of physical medicine and rehabilitation
at Harvard Medical School..
The study is part of a broader effort to collect data on the youngest
epilepsy patients — those younger than 3 years old, the age
at which
epilepsy most often becomes evident.
On June 18, neurosurgeons
at the University of Alabama
at Birmingham implanted a new type of electrical stimulator to control seizures in
patients with difficult - to - control
epilepsy.
When the late Robert Sperry was a neuroscientist
at the California Institute of Technology in Pasadena, he experimented on
patients with
epilepsy, and noticed that breaking the link between brain hemispheres affected the ability to perform certain tasks.
The device, called the RNS System, was implanted April 17, 2014 in a
patient with seizures that previously could not be controlled with medication, or intractable
epilepsy, by Werner Doyle, MD, an associate professor in the Department of Neurosurgery
at NYU Langone.
The way to do so occurred to Olaf Blanke — a neurologist and cognitive neuroscientist
at the Brain - Mind Institute, part of the École Polytechnique Fédérale de Lausanne in Switzerland — a decade ago while he worked with an
epilepsy patient, a 43 - year - old woman with drug - resistant seizures who had to be treated with surgery.
More than 80 % of the
patients had failed
at least two previous
epilepsy medications, and approximately 47 % reported failing 5 or more AEDs.
Rice statistician Marina Vannucci and lead author Sharon Chiang, an M.D. / Ph.D. student
at Rice and Baylor College of Medicine, and their co-authors detailed their technique to analyze brain activity data from
patients with
epilepsy and control groups to see how distinct structures in the brain spontaneously interact.
The study included 35
patients, adults with
epilepsy who currently take lamotrigine, and looked
at long - term dosing using two currently on - market epileptic generic drugs.
This is an electroencephalogram (EEG) of one of the
patients with a Dynamin 1 mutation seen
at the Kiel
epilepsy center.
At UT Southwestern, Dr. Das also examines
epilepsy patients» quality of life and how research treatments are being translated into clinical practice for these
patients.
As a neurologist and epileptologist, Dr. Das is an expert
at using EEG technology to diagnose
patients with
epilepsy, selecting the correct medications, and providing surgical evaluations for qualifying
patients.
A recent paper in the journal
Epilepsy & Behavior describes an
epilepsy patient who had electrodes implanted within her brain
at Emory University Hospital, because neurologists wanted to understand where her seizures were coming from and plan possible surgery.
When a
patient with
epilepsy experiences increased electrical activity in the brain, or seizures, this could be associated with an increase in a range of behaviors, such as hyper - sexuality, hypergraphia (an intense desire to write), hyper - morality and hyper - religiosity, explained Brick Johnstone, professor of health psychology
at Missouri University and lead researcher on the study.
The neurosurgeons
at Penn Medicine's Center for Functional and Restorative Neurosurgery are leaders in breakthrough surgical treatments for
patients with movement disorders including Parkinson's disease, tremor from multiple sclerosis or other causes, dystonia, and medically intractable
epilepsy.
The Gottfried Laboratory in the Departments of Neurology and Psychology
at the University of Pennsylvania is looking to hire a post-doctoral researcher to study the olfactory system using intracranial electrophysiological methods in
patients with medically resistant
epilepsy.
Wilder Penfield was the first neurosurgeon to explore the neural locus of
epilepsy at the same time as mapping behavioral / memory functions of different brain regions through electrical stimulation in fully conscious
patients.
Although it is often suggested that children with
epilepsy who are benefiting from ketogenic dietary therapy continue this for
at least two years, duration of treatment could be shorter in
patients with infantile spasms who become seizure - free; one study reported no adverse effect on seizure outcomes and less risk of growth disturbances when treatment was tapered down after 8 months (15).
Research has been ongoing
at the Mayo Clinic with treatment for
patients with neurological disorders that result in disease (e.g. Parkinson's) or in physical impairments such as
epilepsy and disorder dyspraxia.
We
at RSC are committed to enhancing
patients» quality of care and improving the ability to diagnose and treat seizures and
epilepsy.