Sentences with word «epilepticus»

When the researchers caused status epilepticus in the animals, both the normal and genetically modified mice developed epilepsy.

The super-refractory status epilepticus recurred and was treated anew with the ketogenic diet, but the patient succumbed to a heart attack not likely related to the diet, according to an independent panel.

For the study, the research team recruited 15 patients hospitalized with super-refractory status epilepticus at The Johns Hopkins Hospital, Mayo Clinic, the Queen's Medical Center in Honolulu and Thomas Jefferson University Hospital in Philadelphia.

«An important goal of this field has been to identify the molecular mechanism by which status epilepticus transforms a brain from normal to epileptic,» said McNamara.

Second, the timing of intervention will be important, because the same enzyme has opposing actions a few hours after status epilepticus compared to a couple days later.

It is usually the drug of choice in status epilepticus because it is so effective.

Status epilepticus bears special note.

Status epilepticus seizures, or cluster seizures, are multiple seizures lasting more than five minutes without the dog regaining consciousness.

It can be difficult to distinguish status epilepticus from frequent cluster seizures, but both are life ‑ threatening emergencies.

Onset is usually before the age of five years and multiple different seizure types develop including periods of non-convulsive status epilepticus in some children (2).

Never give your dog oral phenobarbitol if it is experiencing status epilepticus as described above - it needs to be seen by a veterinarian immediately.

SRSE is the most severe form of status epilepticus, under which seizures last for a long time and often recur.

A patient with status epilepticus is initially treated with a class of psychoactive drugs called benzodiazepines.

The late - stage trial was testing Sage's drug, brexanolone, in patients with super-refractory status epilepticus (SRSE) whose seizures persisted despite earlier treatments.

Thirty - four percent of participants reported serious adverse events of which 5 percent were considered treatment related including altered liver enzymes (n = 4), status epilepticus (n = 4), diarrhea (n = 4) and others.

Richard Chin, Director of the University of Edinburgh's Muir Maxwell Epilepsy Centre, who led the study, said: «Our study indicates that children with pre-existing neurological conditions are far more likely to experience chronic neurological and cognitive problems following convulsive status epilepticus.

The study — the first of its kind worldwide — provides insight into the long - term health impact of convulsive status epilepticus (CSE), in which a single seizure, or series of seizures, lasts for at least 30 minutes.

Status epilepticus can spell disaster.

«thirty - three - year - old female, status epilepticus.

«Because there isn't a standard treatment for super-refractory status epilepticus and those patients diagnosed have such a high death and disability rate, we decided we had to try something different to treat them and test its safety and value.»

In animal studies, inducing status epilepticus in an otherwise healthy animal can cause them to become epileptic.

More than 150,000 people in the U.S. each year will develop refractory status epilepticus and, according to published studies, about half of those will develop super-refractory seizures.

«We can only state that it appears to work in some patients to halt status epilepticus and reduces the frequency of their seizures,» says Cervenka.

«This demonstrated that it is possible to intervene following status epilepticus and prevent the animal from becoming epileptic,» McNamara said.

Status epilepticus is often followed by a period of seizure - free recovery before people start to experience recurring temporal lobe seizures.

Super-refractory status epilepticus can occur in people who already have a seizure disorder or in those without such a history.

In the current study, McNamara and his colleagues sought to confirm if TrkB was important for status epilepticus - induced epilepsy.

The prolonged seizures in status epilepticus are therefore thought to cause or importantly contribute to the development of epilepsy in humans.

Retrospective studies of people with severe temporal lobe epilepsy reveal that many of them initially have an episode of prolonged seizures, known as status epilepticus.

Two patients reported their seizures reduced by more than 50 percent, two had ongoing seizures, one had experienced a single seizure and none experienced return of status epilepticus.

In a report on the trials, published online Feb. 8 in Neurology, the investigators conclude that the diet is a «feasible» option for people with so - called super-refractory status epilepticus (SRSE), the most severe seizure classification, in which up to an estimated 60 percent of patients die once they develop this type of seizure.

Status epilepticus is a period of continuous seizures leading to neurodegeneration, used as a model for the development of epilepsy.

The researchers make the case that «inhibiting brain invasion of CCR2 + monocytes could represent a viable method for alleviating several deleterious consequences of status epilepticus.»

Nick Varvel, a postdoc with Ray Dingledine's lab at Emory, was recently presenting his research and showed some photos illustrating the phenomenon of brain inflammation in status epilepticus (prolonged life - threatening seizures).

Four days after status epilepticus, fewer neurons are damaged (bright green) in the neuronal COX - 2 knockout mice.

Monocytes rush into the brain in status epilepticus, and in traumatic brain injury, hemorrhagic stroke and West Nile virus encephalitis, to name some other conditions where brain inflammation is also seen.

In the development of epilepsy, inhibiting COX - 2 turns out to be complicated as well. Ray Dingledine, chair of pharmacology at Emory, and colleagues have a new paper showing that COX - 2 has both protective and harmful effects in mice after status epilepticus, depending on the timing and what cells the enzyme comes from.

Two weeks later, Dr. Johnson and his team had a breakthrough when an electroencephalogram, or EEG, revealed recurring seizures in Donna's brain that were unaccompanied by physical symptoms — a serious condition, known as nonconvulsive status epilepticus, that kills 56 % of the people it affects.

HHV - 6 has also been tied to febrile seizures and status epilepticus.

We also start anticonvulsants immediately in any patient that has status epilepticus or cluster seizures from the beginning.

These can become life - threatening because they can progress into status epilepticus.

This is called status epilepticus.

We might also give you a valium solution, to be given via rectum if your dog starts the continual seizure seen in status epilepticus.

An injectable version of this drug given intravenously (IV) to stop status epilepticus.