Perinatal immune activation produces persistent sleep alterations and
epileptiform activity in male mice Missig G, Mokler EL, Robbins JO, Alexander AJ, McDougle CJ, Carlezon WA.
Dr. Palop discovered that mice genetically engineered to simulate AD (hAPP mice) develop aberrant excitatory patterns of neuronal network activity, including network hypersynchrony,
epileptiform activity, and seizures.
Discovered that mouse models of AD (APP mice) develop aberrant patterns of neuronal network activity, including network hypersynchrony,
epileptiform activity, and seizures.
Not exact matches
Levetiracetam may act by preventing hypersynchronization of
epileptiform burst firing and propagation of seizure
activity.