Radiographic signs of epiphyseal dysgenesis (underdeveloped epiphyses throughout the long bones), shortened vertebral bodies, and delayed
epiphyseal closure are common.
Other useful diagnostic aids include comparison of height with that of littermates, evidence of delayed
epiphyseal closure or dysgenesis on skeletal radiographs, and skin biopsy.
Not exact matches
At puberty, oestrogen promotes skeletal maturation and the gradual, progressive
closure of the
epiphyseal growth plate, possibly as a consequence of both oestrogen - induced vascular and osteoplastic invasion and the termination of chondrogenesis.