Sentences with phrase «epistatic interactions»
Epistatic interactions refer to the way in which genes interact with one another to influence a particular trait or characteristic. It means that the effect of one gene depends on another gene's presence or absence. Basically, when genes interact epistatically, they can either enhance or suppress each other's effects, affecting the outcome. Full definition
More specifically, we use large - scale data acquisition and quantitative modelling of phenotypes and molecular profiles, systematic perturbations (such as drugs or high - throughput genetics) and computational analysis of non-linear, epistatic interaction networks.
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According to Greene and colleagues [121], real associations may not replicate in independent samples if they are part of a larger epistatic interaction.