Work in our group is aimed to understand the cellular, molecular and genetic mechanisms that control the establishment and maintenance of
epithelial cell polarity.
Alexandra Kumichel (Knust, MPG)-- «
Epithelial cell polarity in the embryonic hindgut of Drosophila melanogaster» (2013)
Nadine Muschalik (Knust, MPG)-- «
Epithelial cell polarity and photoreceptor morphogenesis in Drosophila» (2010)
Jennifer Fish (Huttner, MPG)-- «The evolution of neuronal progenitor cell division in mammals: the role of the abnormal spindle - like microcephaly associated (Aspm) protein and
epithelial cell polarity» (2007)
Not exact matches
Alix therefore functions as a «molecular bridge» that also determines the
polarity of individual
epithelial cells, namely the way
cells are oriented with respect to one another within the
epithelial cell layer.
A molecular mechanism directly linking E-cadherin adhesion to initiation of
epithelial cell surface
polarity.
Nucleofection disrupts tight junction fence function to alter membrane
polarity of renal
epithelial cells.
Anne - Kathrin Classen (Eaton, MPG)-- «Hexagonal packing of Drosophila wing
epithelial cells by the planar
cell polarity pathway» (2006)
Tumor necrosis factor alpha and inflammation disrupt the
polarity complex in intestinal
epithelial cells by a posttranslational mechanism.
Sponge
cells adhere to form tissue - like layers, but a true
epithelial cell layer, characterized by aligned
cell polarity, belt - form junctions and underlying basal lamina, is thought to be a eumetazoan innovation.
Yohanns Bellaiche's teams,
Polarity Division Morphogenesis --(CNRS / Inserm / Institut Curie), works on the organisation of tissue
cells just published its latest results in the revue Nature:
Epithelial tricellular junctions act as interphase...
Carcinomas arise from
epithelial cells, and tumor progression involves a loss of
polarity, so an understanding of
cell polarity is important in the identification of novel therapeutic approaches to cancer.
We have previously reported that these KD
cells are partially transformed as evidenced by the disruption of
epithelial polarity and morphological differentiation in the 3D IrECM (He et al., 2008).